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How to get fromDestin to Columbiaby plane, taxi, bus, train, or car

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There are 6 ways to get from Destin to Columbia by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Destin–Fort Walton Beach Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Columbia (CAE)plane plane VPS - CAE
    5h 10m
    $185–852

  2. Drive 462.5 mi

    cheapest
    1. Drive from Destin to Columbiacar car 462.5 mi
    9h 29m
    $85–122

  3. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Jacksonvillebus bus
    4. Take the train from Jacksonville to Columbia Stationtrain train
    15h 31m
    $253–415

  4. Taxi to Northwest Florida Beaches International Airport, fly

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Columbia (CAE)plane plane ECP - CAE
    6h 29m
    $289–975

  5. Taxi to Pensacola International Airport, fly

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Columbia (CAE)plane plane PNS - CAE
    6h 39m
    $250–904

  6. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Jacksonvillebus bus
    4. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    5. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Senate Northbus bus 44
    18h 3m
    $209–319

Destin–Fort Walton Beach Airport (VPS) to Columbia (CAE) flights

Calendar61Weekly Planes
Duration4h 39mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

Map of how to get from Destin to Columbia.ExpandLaunch map view
  • Distance: 421.3 mi
  • Duration: 5h 10m

What companies run services between Destin, FL, USA and Columbia, SC, USA?

Delta and American Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Columbia (CAE) every 3 hours.

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