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How to get fromDestin to Fort Myersby plane, taxi, bus, or car

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There are 8 ways to get from Destin to Fort Myers by plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Ft. Myers

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW)plane plane VPS - RSW
    6h 22m
    $141–605

  2. Drive  502.1 mi

    cheapest
    1. Drive from Destin to Fort Myerscar car 502.1 mi
    9h 33m
    $92–133

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Fort Myersbus bus Houston
    11h 8m
    $184–230

  4. Taxi to Northwest Florida Beaches International Airport, fly to Ft. Myers

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW)plane plane ECP - RSW
    6h 57m
    $245–728

  5. Fly Destin–Fort Walton Beach Airport to Miami International Airport, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane plane VPS - MIA
    2. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    6h 56m
    $123–440

  6. Taxi to Pensacola International Airport, fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane PNS - FLL
    3. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    6h 33m
    $279–477

  7. Taxi to Pensacola International Airport, fly to Miami International Airport, bus

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)plane plane PNS - MIA
    3. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    7h 32m
    $208–522

  8. Taxi to Pensacola International Airport, fly to Tampa, bus

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Tampa (TPA)plane plane PNS - TPA
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    7h 53m
    $361–619

Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW) flights

Calendar54Weekly Planes
Duration5h 34mAverage Duration
Ticket$97Cheapest Price
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Comparing Your Travel Options

Map of how to get from Destin to Fort Myers.ExpandLaunch map view
  • Distance: 430.3 mi
  • Duration: 6h 22m

What companies run services between Destin, FL, USA and Fort Myers, FL, USA?

Delta, Southwest Airlines, and American Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW) every 4 hours.

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