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How to get fromDestin to Jefferson Cityby plane, shuttle, taxi, bus, train, or car

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There are 8 ways to get from Destin to Jefferson City by plane, shuttle, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Lambert–St. Louis International Airport, shuttle

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL)plane plane VPS - STL
    2. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    5h 15m
    $278–750

  2. Drive 789.9 mi

    cheapest
    1. Drive from Destin to Jefferson Citycar car 789.9 mi
    15h 56m
    $145–209

  3. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    5. Take the train from St. Louis to Jefferson City Stationtrain train
    25h 12m
    $326–507

  4. Fly Destin–Fort Walton Beach Airport to Columbia Regional Airport

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU)plane plane VPS - COU
    2h 56m
    $203–540

  5. Taxi to Northwest Florida Beaches International Airport, fly to Lambert–St. Louis International Airport, shuttle

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL)plane plane ECP - STL
    3. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    5h 53m
    $382–873

  6. Taxi to Pensacola International Airport, fly to Lambert–St. Louis International Airport, shuttle

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane plane PNS - STL
    3. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    6h 2m
    $348–772

  7. Fly Destin–Fort Walton Beach Airport to Midamerica St. Louis Airport, train

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    2. Take the train from St. Louis to Jefferson City Stationtrain train
    6h 44m
    $169–522

  8. Taxi, bus, train via Atlanta

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    5. Take the train from St. Louis to Jefferson City Stationtrain train
    25h 47m
    $301–512

Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL) flights

Calendar18Weekly Planes
Duration3h 33mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Destin to Jefferson City.ExpandLaunch map view
  • Distance: 741.3 mi
  • Duration: 5h 15m

What companies run services between Destin, FL, USA and Jefferson City, MO, USA?

Allegiant Air flies from Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU) twice a week.

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