Rome2Rio

How to get fromDestin to Jefferson Cityby plane, taxi, bus, train, car, or shuttle

Find Transport to Jefferson City

See all options

There are 9 ways to get from Destin to Jefferson City by plane, taxi, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Columbia Regional Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU)plane plane VPS - COU
    2h 49m
    $203–550

  2. Drive  789.9 mi

    cheapest
    1. Drive from Destin to Jefferson Citycar car 789.9 mi
    15h 56m
    $145–209

  3. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    5. Take the train from St. Louis to Jefferson City Stationtrain train
    25h 52m
    $286–457

  4. Fly Destin–Fort Walton Beach Airport to Lambert–St. Louis International Airport, shuttle

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL)plane plane VPS - STL
    2. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    5h 20m
    $268–750

  5. Taxi to Northwest Florida Beaches International Airport, fly to Lambert–St. Louis International Airport, shuttle

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL)plane plane ECP - STL
    3. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    5h 53m
    $377–873

  6. Taxi to Pensacola International Airport, fly to Lambert–St. Louis International Airport, shuttle

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane plane PNS - STL
    3. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    6h 2m
    $348–782

  7. Fly Destin–Fort Walton Beach Airport to Midamerica St. Louis Airport, train

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    2. Take the train from St. Louis to Jefferson City Stationtrain train
    6h 44m
    $164–537

  8. Fly Destin–Fort Walton Beach Airport to Northwest Arkansas Regional Airport, drive

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Northwest Arkansas Regional Airport (XNA)plane plane VPS - XNA
    2. Drive from Northwest Arkansas Regional Airport (XNA) to Jefferson Citycar car
    6h 58m
    $193–765

  9. Taxi, bus, train via Atlanta

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    5. Take the train from St. Louis to Jefferson City Stationtrain train
    26h 47m
    $291–462

Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU) flights

Calendar2Weekly Planes
Duration1h 59mAverage Duration
Ticket$72Cheapest Price
See schedules

Questions & Answers

Map of how to get from Destin to Jefferson City.ExpandLaunch map view
  • Distance: 697 mi
  • Duration: 2h 49m

What companies run services between Destin, FL, USA and Jefferson City, MO, USA?

Allegiant Air flies from Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU) twice a week.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound