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How to get fromDestin to Jefferson Cityby plane, shuttle, taxi, bus, train, or car

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There are 7 ways to get from Destin to Jefferson City by plane, shuttle, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport, shuttle

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL)plane plane VPS - STL
    2. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    5h 20m
    $268–750

  2. Drive  789.9 mi

    cheapest
    1. Drive from Destin to Jefferson Citycar car 789.9 mi
    15h 56m
    $135–195

  3. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    5. Take the train from St. Louis to Jefferson City Stationtrain train
    25h 52m
    $341–512

  4. Fly to Columbia Regional Airport

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU)plane plane VPS - COU
    2h 49m
    $203–550

  5. Fly to Midamerica St. Louis Airport, train

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    2. Take the train from St. Louis to Jefferson City Stationtrain train
    6h 44m
    $199–572

  6. Taxi, bus, train via Atlanta

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    5. Take the bus from Carbondale to St. Louisbus bus
    6. Take the train from St. Louis to Jefferson City Stationtrain train
    27h 13m
    $331–500

  7. Taxi, bus, train via Atlanta #2

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    5. Take the train from St. Louis to Jefferson City Stationtrain train
    27h 32m
    $336–527

Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL) flights

Calendar32Weekly Planes
Duration4hAverage Duration
Ticket$92Cheapest Price
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Comparing Your Travel Options

Map of how to get from Destin to Jefferson City.ExpandLaunch map view
  • Distance: 741.3 mi
  • Duration: 5h 20m

What companies run services between Destin, FL, USA and Jefferson City, MO, USA?

Allegiant Air flies from Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU) twice a week.

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