Rome2Rio

How to get fromDestin to Kissimmeeby taxi, plane, bus, car, or train

Find Transport to Kissimmee

See all options

There are 9 ways to get from Destin to Kissimmee by taxi, plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Pensacola International Airport, fly to Orlando

    best
    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Orlando (MCO)plane plane PNS - MCO
    4h 20m
    $217–1,058

  2. Drive 392.5 mi

    cheapest
    1. Drive from Destin to Kissimmeecar car 392.5 mi
    7h 30m
    $72–104

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Orlandobus bus
    10h 59m
    $178–244

  4. Fly Destin–Fort Walton Beach Airport to Orlando

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Orlando (MCO)plane plane VPS - MCO
    5h 52m
    $117–426

  5. Taxi to Northwest Florida Beaches International Airport, fly to Orlando

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Orlando (MCO)plane plane ECP - MCO
    6h 35m
    $221–539

  6. Taxi to Pensacola International Airport, fly to Tampa, train

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Tampa (TPA)plane plane PNS - TPA
    3. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    6h 25m
    $318–708

  7. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Lakelandbus bus
    4. Take the train from Lakeland Amtrak Station to Kissimmee Amtrak Stationtrain train
    11h 16m
    $196–259

  8. Taxi, bus via Mccoy Rd & Gondola Dr

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee - FSU - Old St Augustine at Intramural Field to Orlando - RedCoach Station, FLbus bus
    11h 25m
    $207–310

  9. Taxi, bus via Gainesville

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Gainesville Bus Stopbus bus
    4. Take the bus from Gainesville Bus Stop to Orlando Bus Stationbus bus
    5. Take the bus from N Garland Ave & W Amelia St to N Central Ave & W Cherry Stbus bus 18
    14h 5m
    $179–254

Pensacola International Airport (PNS) to Orlando (MCO) flights

Calendar46Weekly Planes
Duration2h 46mAverage Duration
Ticket$64Cheapest Price
See schedules

Questions & Answers

Map of how to get from Destin to Kissimmee.ExpandLaunch map view
  • Distance: 449.8 mi
  • Duration: 4h 20m

What companies run services between Destin, FL, USA and Kissimmee, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Orlando (MCO) every 3 hours.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound