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How to get fromDestin to Melroseby taxi, bus, car, or plane

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There are 6 ways to get from Destin to Melrose by taxi, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus

    best
    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Gainesvillebus bus
    7h 37m
    $220–287

  2. Drive 297.2 mi

    cheapest
    1. Drive from Destin to Melrosecar car 297.2 mi
    6h 3m
    $55–79

  3. Fly from Destin–Fort Walton Beach Airport

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Gainesville Regional Airport (GNV)plane plane VPS - GNV
    5h 10m
    $173–495

  4. Taxi, bus via SR 26 & N Main St

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Gainesville Bus Stopbus bus
    11h 1m
    $181–247

  5. Taxi to Northwest Florida Beaches International Airport, fly

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Gainesville Regional Airport (GNV)plane plane ECP - GNV
    5h 18m
    $272–618

  6. Taxi to Pensacola International Airport, fly

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Gainesville Regional Airport (GNV)plane plane PNS - GNV
    5h 2m
    $248–547

Destin–Fort Walton Beach Airport (VPS) to Gainesville Regional Airport (GNV) flights

Calendar55Weekly Planes
Duration5h 34mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from Destin to Melrose.ExpandLaunch map view
  • Distance: 349.5 mi
  • Duration: 7h 37m

What companies run services between Destin, FL, USA and Melrose, FL, USA?

Delta and American Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Gainesville Regional Airport (GNV) every 4 hours.

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