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How to get fromDestin to Mississippiby taxi, plane, bus, train, or car

Find Transport to Mississippi

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There are 4 ways to get from Destin to Mississippi by taxi, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly

    best
    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Memphis (MEM)plane plane PNS - MEM
    2h 58m
    $280–979

  2. Drive  290 mi

    cheapest
    1. Drive from Destin to Jacksoncar car 290 mi
    5h 30m
    $50–72

  3. Taxi, bus, train

    1. Take the taxi from Destin to Downtown Transfer Stationtaxi taxi
    2. Take the taxi from Blue Angel Pkwy & Gulf Beach Hwy to Mobiletaxi taxi
    3. Take the bus from Mobile to Biloxibus bus
    4. Take the bus from Biloxi Transit Center to New Orleans Bus Stationbus bus
    5. Take the train from New Orleans Union Passenger Terminal to Jacksontrain train
    12h 48m
    $392–535

  4. Taxi, bus, train via Pascagoula

    1. Take the taxi from Destin to Downtown Transfer Stationtaxi taxi
    2. Take the taxi from Blue Angel Pkwy & Gulf Beach Hwy to Mobiletaxi taxi
    3. Take the bus from Mobile to Pascagoulabus bus
    4. Take the train from Pascagoula, MS to New Orleans, LA - Union Passenger Terminaltrain train
    5. Take the train from New Orleans Union Passenger Terminal to Jacksontrain train
    13h 8m
    $423–585

Pensacola International Airport (PNS) to Memphis (MEM) flights

Calendar39Weekly Planes
Duration3h 28mAverage Duration
Ticket$135Cheapest Price
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Comparing Your Travel Options

Map of how to get from Destin to Mississippi.ExpandLaunch map view
  • Distance: 412.6 mi
  • Duration: 2h 58m

What companies run services between Destin, FL, USA and Mississippi, USA?

There is no direct connection from Destin to Mississippi. However, you can take the taxi to Pensacola-Airport-PNS airport, fly to Memphis (MEM), then take the taxi to Southaven. Alternatively, you can take the taxi to Downtown Transfer Station, take the line 58 bus to Blue Angel Pkwy & Gulf Beach Hwy, take the taxi to Mobile, take the bus to Biloxi, walk to Biloxi Transit Center, take the bus to New Orleans Bus Station, walk to New Orleans Union Passenger Terminal, then take the train to Jackson.

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