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How to get fromDestin to Mount Pleasantby plane, taxi, bus, train, or car

Find Transport to Mount Pleasant

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There are 6 ways to get from Destin to Mount Pleasant by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Destin–Fort Walton Beach Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Charleston International Airport (CHS)plane plane VPS - CHS
    7h 8m
    $112–424

  2. Drive 491 mi

    cheapest
    1. Drive from Destin to Mount Pleasantcar car 491 mi
    9h 57m
    $90–130

  3. Taxi, bus, train via Tallahassee

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Jacksonvillebus bus
    4. Take the train from Jacksonville to Charleston Amtrak Stationtrain train
    14h 25m
    $282–445

  4. Taxi to Northwest Florida Beaches International Airport, fly

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Charleston International Airport (CHS)plane plane ECP - CHS
    7h 25m
    $216–547

  5. Taxi to Pensacola International Airport, fly

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Charleston International Airport (CHS)plane plane PNS - CHS
    8h
    $492–1,356

  6. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Wildwoodbus bus
    3. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    4. Take the train from Jacksonville to Charleston Amtrak Stationtrain train
    19h 47m
    $290–441

Destin–Fort Walton Beach Airport (VPS) to Charleston International Airport (CHS) flights

Calendar55Weekly Planes
Duration4h 25mAverage Duration
Ticket$67Cheapest Price
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Questions & Answers

Map of how to get from Destin to Mount Pleasant.ExpandLaunch map view
  • Distance: 454.6 mi
  • Duration: 7h 8m

What companies run services between Destin, FL, USA and Mount Pleasant, SC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Destin–Fort Walton Beach Airport (VPS) to Charleston International Airport (CHS) every 4 hours.

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