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How to get fromDestin to Panama Cityby plane, car, or taxi

Find Transport to Panama City

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There are 4 ways to get from Destin to Panama City by plane, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Destin–Fort Walton Beach Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Tocumen International Airport (PTY)plane plane VPS - PTY
    8h 9m
    $191–638

  2. Drive  5,227.3 km

    1. Drive from Destin to Panama Citycar car 5,227.3 km
    2d 22h
    $716–1,033

  3. Taxi to Pensacola International Airport, fly

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Tocumen International Airport (PTY)plane plane PNS - PTY
    8h 14m
    $266–670

  4. Taxi to Northwest Florida Beaches International Airport, fly

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Tocumen International Airport (PTY)plane plane ECP - PTY
    8h 58m
    $315–811

Destin–Fort Walton Beach Airport (VPS) to Tocumen International Airport (PTY) flights

Calendar29Weekly Planes
Duration8h 5mAverage Duration
Ticket$118Cheapest Price
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Comparing Your Travel Options

Map of how to get from Destin to Panama City.ExpandLaunch map view
  • Distance: 2,545.7 km
  • Duration: 8h 9m

What companies run services between Destin, FL, USA and Panama City, Panama?

American Airlines, Delta, and three other airlines fly from Destin–Fort Walton Beach Airport (VPS) to Tocumen International Airport (PTY) 4 times a day.

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