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How to get fromDestin to Poplar Bluffby plane, train, taxi, bus, or car

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There are 9 ways to get from Destin to Poplar Bluff by plane, train, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Lambert–St. Louis International Airport, train

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL)plane plane VPS - STL
    2. Take the train from St. Louis to Poplar Bluff Stationtrain train
    7h 45m
    $196–713

  2. Drive 612.5 mi

    cheapest
    1. Drive from Destin to Poplar Bluffcar car 612.5 mi
    11h 30m
    $112–162

  3. Taxi, bus, drive

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Tornado Bus Co - Nashville to Tornado Bus Co - West Memphisbus bus
    5. Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus bus
    6. Drive from Flying J - Matthews to Poplar Bluffcar car
    24h 55m
    $323–639

  4. Fly Destin–Fort Walton Beach Airport to Midamerica St. Louis Airport, train

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    2. Take the train from St. Louis to Poplar Bluff Stationtrain train
    8h 7m
    $184–552

  5. Taxi to Pensacola International Airport, fly to Cape Girardeau Municipal Airport, drive

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Cape Girardeau Municipal Airport (CGI)plane plane PNS - CGI
    3. Drive from Cape Girardeau Municipal Airport (CGI) to Poplar Bluffcar car
    4h 34m
    $260–641

  6. Taxi to Northwest Florida Beaches International Airport, fly to Lambert–St. Louis International Airport, train

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL)plane plane ECP - STL
    3. Take the train from St. Louis to Poplar Bluff Stationtrain train
    8h 23m
    $300–836

  7. Taxi to Pensacola International Airport, fly to Lambert–St. Louis International Airport, train

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane plane PNS - STL
    3. Take the train from St. Louis to Poplar Bluff Stationtrain train
    8h 32m
    $271–765

  8. Taxi, bus, train

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    5. Take the train from St. Louis to Poplar Bluff Stationtrain train
    27h 9m
    $306–527

  9. Taxi, bus, train via Atlanta

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    5. Take the train from St. Louis to Poplar Bluff Stationtrain train
    28h 9m
    $311–537

Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL) flights

Calendar18Weekly Planes
Duration3h 33mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

Map of how to get from Destin to Poplar Bluff.ExpandLaunch map view
  • Distance: 802.2 mi
  • Duration: 7h 45m

What companies run services between Destin, FL, USA and Poplar Bluff, MO, USA?

There is no direct connection from Destin to Poplar Bluff. However, you can take the taxi to Destin–Fort Walton Beach Airport (VPS) airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, take the train to CIVIC CENTER station, walk to St. Louis, then take the train to Poplar Bluff Station. Alternatively, you can take the taxi to Crestview, take the bus to Tallahassee, walk to N Monroe Street and Silver Slipper Lane, take the bus to C.K. Steele Plaza Gate 22, take the bus to Nashville Bus Station, walk to Fulton Station Outbound, take the line 52 bus to Walmart Station Outbound, walk to Tornado Bus Co - Nashville, take the bus to Tornado Bus Co - West Memphis, take the bus to Flying J - Matthews, then drive to Poplar Bluff.

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