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How to get fromDestin to San Antonioby plane, taxi, bus, train, or car

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There are 8 ways to get from Destin to San Antonio by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to San Antonio International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to San Antonio International Airport (SAT)plane plane VPS - SAT
    5h 11m
    $140–602

  2. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Houston Bus Stationbus bus
    4. Take the bus from Houston Bus Station to San Antonio Bus Stationbus bus
    24h 32m
    $296–427

  3. Taxi, bus, train

    1. Take the taxi from Destin to Downtown Transfer Stationtaxi taxi
    2. Take the taxi from Blue Angel Pkwy & Gulf Beach Hwy to Mobiletaxi taxi
    3. Take the bus from Mobile to Pascagoulabus bus
    4. Take the train from Pascagoula, MS to New Orleans, LA - Union Passenger Terminaltrain train
    5. Take the train from New Orleans Union Passenger Terminal to San Antonio Stationtrain train
    24h 34m
    $633–915

  4. Drive  765.3 mi

    1. Drive from Destin to San Antoniocar car 765.3 mi
    12h 51m
    $140–202

  5. Taxi to Pensacola International Airport, fly to San Antonio International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to San Antonio International Airport (SAT)plane plane PNS - SAT
    4h 3m
    $220–704

  6. Taxi to Northwest Florida Beaches International Airport, fly to San Antonio International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to San Antonio International Airport (SAT)plane plane ECP - SAT
    6h
    $249–725

  7. Fly Destin–Fort Walton Beach Airport to Austin-Bergstrom International Airport, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Austin-Bergstrom International Airport (AUS)plane plane VPS - AUS
    2. Take the bus from Austin, TX - UT Austin to San Antonio, TX - E Commerce Stbus bus
    8h 2m
    $148–550

  8. Taxi, bus via Bellaire

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Houston Bus Stationbus bus
    4. Take the bus from Hyatt Regency Galleria Houston to San Antoniobus bus
    25h 20m
    $398–525

Destin–Fort Walton Beach Airport (VPS) to San Antonio International Airport (SAT) flights

Calendar90Weekly Planes
Duration5h 40mAverage Duration
Ticket$99Cheapest Price
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Comparing Your Travel Options

Map of how to get from Destin to San Antonio.ExpandLaunch map view
  • Distance: 740.7 mi
  • Duration: 5h 11m

What companies run services between Destin, FL, USA and San Antonio, TX, USA?

Southwest Airlines, American Airlines, and Delta fly from Destin–Fort Walton Beach Airport (VPS) to San Antonio International Airport (SAT) hourly.

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