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How to get fromDestin to San Antonioby plane, taxi, bus, train, or car

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There are 8 ways to get from Destin to San Antonio by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to San Antonio International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to San Antonio International Airport (SAT)plane plane VPS - SAT
    4h 46m
    $145–602

  2. Drive 765.3 mi

    cheapest
    1. Drive from Destin to San Antoniocar car 765.3 mi
    12h 51m
    $140–202

  3. Taxi, bus, train

    1. Take the taxi from Destin to Downtown Transfer Stationtaxi taxi
    2. Take the taxi from Blue Angel Pkwy & Gulf Beach Hwy to Mobiletaxi taxi
    3. Take the bus from Mobile to Pascagoulabus bus
    4. Take the train from Pascagoula, MS to New Orleans, LA - Union Passenger Terminaltrain train
    5. Take the train from New Orleans Union Passenger Terminal to San Antonio Stationtrain train
    24h 34m
    $483–785

  4. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Houston Bus Stationbus bus
    4. Take the bus from Houston Bus Station to San Antonio Bus Stationbus bus
    24h 57m
    $276–452

  5. Taxi to Pensacola International Airport, fly to San Antonio International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to San Antonio International Airport (SAT)plane plane PNS - SAT
    4h 16m
    $380–1,154

  6. Taxi to Northwest Florida Beaches International Airport, fly to San Antonio International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to San Antonio International Airport (SAT)plane plane ECP - SAT
    5h 30m
    $259–725

  7. Taxi to Northwest Florida Beaches International Airport, fly to Austin-Bergstrom International Airport, bus

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Austin-Bergstrom International Airport (AUS)plane plane ECP - AUS
    3. Take the bus from Austin Eastside Bus Plaza to San Antonio Bus Stationbus bus
    6h 12m
    $261–751

  8. Taxi, bus via Bellaire

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Houston Bus Stationbus bus
    4. Take the bus from Hyatt Regency Galleria Houston to San Antoniobus bus
    25h 45m
    $378–545

Destin–Fort Walton Beach Airport (VPS) to San Antonio International Airport (SAT) flights

Calendar65Weekly Planes
Duration5h 9mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

Map of how to get from Destin to San Antonio.ExpandLaunch map view
  • Distance: 740.7 mi
  • Duration: 4h 46m

What companies run services between Destin, FL, USA and San Antonio, TX, USA?

Southwest Airlines, American Airlines, and Delta fly from Destin–Fort Walton Beach Airport (VPS) to San Antonio International Airport (SAT) every 3 hours.

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