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How to get fromDestin to San Franciscoby plane, taxi, bus, train, or car

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There are 8 ways to get from Destin to San Francisco by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to San Francisco International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to San Francisco International Airport (SFO)plane plane VPS - SFO
    8h 7m
    $152–522

  2. Taxi, bus, train, Caltrain

    1. Take the taxi from Destin to Downtown Transfer Stationtaxi taxi
    2. Take the taxi from Blue Angel Pkwy & Gulf Beach Hwy to Mobiletaxi taxi
    3. Take the bus from Mobile to Pascagoulabus bus
    4. Take the train from Pascagoula, MS to New Orleans, LA - Union Passenger Terminaltrain train
    5. Take the train from New Orleans Union Passenger Terminal to Los Angelestrain train
    6. Take the train from Los Angeles to San Josetrain train
    7. Take the train from San Jose Diridon Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    2d 20h
    $1,562–2,497

  3. Drive  2,411.8 mi

    1. Drive from Destin to San Franciscocar car 2,411.8 mi
    39h 56m
    $413–596

  4. Taxi to Pensacola International Airport, fly to Oakland International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Oakland International Airport (OAK)plane plane PNS - OAK
    9h 1m
    $263–710

  5. Taxi to Pensacola International Airport, fly to San Francisco International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to San Francisco International Airport (SFO)plane plane PNS - SFO
    8h 47m
    $247–474

  6. Taxi to Northwest Florida Beaches International Airport, fly to Oakland International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Oakland International Airport (OAK)plane plane ECP - OAK
    9h 58m
    $292–781

  7. Fly Destin–Fort Walton Beach Airport to Norman Y. Mineta San José International Airport, Caltrain

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Norman Y. Mineta San José International Airport (SJC)plane plane VPS - SJC
    2. Take the train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    9h 50m
    $205–765

  8. Fly Destin–Fort Walton Beach Airport to Oakland International Airport

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Oakland International Airport (OAK)plane plane VPS - OAK
    7h 59m
    $178–658

Destin–Fort Walton Beach Airport (VPS) to San Francisco International Airport (SFO) flights

Calendar58Weekly Planes
Duration8h 51mAverage Duration
Ticket$109Cheapest Price
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Comparing Your Travel Options

Map of how to get from Destin to San Francisco.ExpandLaunch map view
  • Distance: 2,125.9 mi
  • Duration: 8h 7m

What companies run services between Destin, FL, USA and San Francisco, CA, USA?

American Airlines, Delta, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to San Francisco International Airport (SFO) every 4 hours.

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