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How to get fromDestin to San Franciscoby plane, taxi, bus, train, or car

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There are 6 ways to get from Destin to San Francisco by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to San Francisco International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to San Francisco International Airport (SFO)plane plane VPS - SFO
    8h 25m
    $172–542

  2. Taxi, bus, train, Caltrain

    1. Take the taxi from Destin to Downtown Transfer Stationtaxi taxi
    2. Take the taxi from Blue Angel Pkwy & Gulf Beach Hwy to Mobiletaxi taxi
    3. Take the bus from Mobile to Pascagoulabus bus
    4. Take the train from Pascagoula, MS to New Orleans, LA - Union Passenger Terminaltrain train
    5. Take the train from New Orleans Union Passenger Terminal to Los Angelestrain train
    6. Take the train from Los Angeles to San Josetrain train
    7. Take the train from San Jose Diridon Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    2d 20h
    $1,092–1,997

  3. Drive 2,411.8 mi

    1. Drive from Destin to San Franciscocar car 2,411.8 mi
    39h 56m
    $441–636

  4. Fly Destin–Fort Walton Beach Airport to Oakland International Airport

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Oakland International Airport (OAK)plane plane VPS - OAK
    8h 9m
    $238–858

  5. Taxi to Pensacola International Airport, fly to San Francisco International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to San Francisco International Airport (SFO)plane plane PNS - SFO
    8h 21m
    $237–484

  6. Taxi to Pensacola International Airport, fly to Oakland International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Oakland International Airport (OAK)plane plane PNS - OAK
    8h 31m
    $293–710

Destin–Fort Walton Beach Airport (VPS) to San Francisco International Airport (SFO) flights

Calendar26Weekly Planes
Duration9h 11mAverage Duration
Ticket$123Cheapest Price
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Questions & Answers

Map of how to get from Destin to San Francisco.ExpandLaunch map view
  • Distance: 2,125.9 mi
  • Duration: 8h 25m

What companies run services between Destin, FL, USA and San Francisco, CA, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Destin–Fort Walton Beach Airport (VPS) to San Francisco International Airport (SFO) 4 times a day.

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