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How to get fromDestin to Sanibelby plane, taxi, bus, or car

Find Transport to Sanibel

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There are 5 ways to get from Destin to Sanibel by plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Destin–Fort Walton Beach Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW)plane plane VPS - RSW
    5h 6m
    $203–565

  2. Drive 518.6 mi

    cheapest
    1. Drive from Destin to Sanibelcar car 518.6 mi
    9h 59m
    $95–137

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Fort Myersbus bus Houston
    11h 42m
    $244–310

  4. Taxi to Northwest Florida Beaches International Airport, fly

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW)plane plane ECP - RSW
    5h 45m
    $307–688

  5. Taxi to Pensacola International Airport, fly

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Ft. Myers (RSW)plane plane PNS - RSW
    5h 54m
    $573–1,047

Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW) flights

Calendar56Weekly Planes
Duration5h 34mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Destin to Sanibel.ExpandLaunch map view
  • Distance: 440.3 mi
  • Duration: 5h 6m

What companies run services between Destin, FL, USA and Sanibel, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW) every 4 hours.

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