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How to get fromDestin to Sanibelby plane, taxi, bus, or car

Find Transport to Sanibel

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There are 6 ways to get from Destin to Sanibel by plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Ft. Myers

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW)plane plane VPS - RSW
    4h 50m
    $203–615

  2. Drive 518.6 mi

    cheapest
    1. Drive from Destin to Sanibelcar car 518.6 mi
    9h 59m
    $95–137

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Fort Myersbus bus Houston
    11h 42m
    $244–305

  4. Taxi to Northwest Florida Beaches International Airport, fly to Ft. Myers

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW)plane plane ECP - RSW
    5h 54m
    $307–738

  5. Taxi to Pensacola International Airport, fly to Ft. Myers

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Ft. Myers (RSW)plane plane PNS - RSW
    5h 51m
    $568–1,037

  6. Fly Destin–Fort Walton Beach Airport to Miami International Airport, bus, taxi

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane plane VPS - MIA
    2. Take the bus from Miami Airport to Fort Myers 7-11bus bus
    3. Take the taxi from Fort Myers 7-11 to Sanibeltaxi taxi
    6h 41m
    $213–580

Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW) flights

Calendar49Weekly Planes
Duration5h 30mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Destin to Sanibel.ExpandLaunch map view
  • Distance: 440.3 mi
  • Duration: 4h 50m

What companies run services between Destin, FL, USA and Sanibel, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW) every 4 hours.

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