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How to get fromDestin to Sanibel Islandby plane, taxi, bus, or car

Find Transport to Sanibel Island

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There are 5 ways to get from Destin to Sanibel Island by plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Destin–Fort Walton Beach Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW)plane plane VPS - RSW
    5h 3m
    $203–560

  2. Drive 517.5 mi

    cheapest
    1. Drive from Destin to Sanibel Islandcar car 517.5 mi
    9h 57m
    $95–137

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Fort Myersbus bus Houston
    11h 40m
    $244–305

  4. Taxi to Northwest Florida Beaches International Airport, fly

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW)plane plane ECP - RSW
    5h 43m
    $307–683

  5. Taxi to Pensacola International Airport, fly

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Ft. Myers (RSW)plane plane PNS - RSW
    5h 52m
    $573–1,042

Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW) flights

Calendar56Weekly Planes
Duration5h 34mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Destin to Sanibel Island.ExpandLaunch map view
  • Distance: 439.3 mi
  • Duration: 5h 3m

What companies run services between Destin, FL, USA and Sanibel Island, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW) every 4 hours.

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