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How to get fromDestin to Spartanburgby plane, taxi, bus, or car

Find Transport to Spartanburg

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There are 6 ways to get from Destin to Spartanburg by plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Greenville–Spartanburg International Airport (GSP)plane plane VPS - GSP
    4h 2m
    $183–670

  2. Drive  474.9 mi

    cheapest
    1. Drive from Destin to Spartanburgcar car 474.9 mi
    9h 25m
    $87–126

  3. Taxi, bus via Greenville

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Greenvillebus bus
    14h 49m
    $268–367

  4. Taxi to Northwest Florida Beaches International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Greenville–Spartanburg International Airport (GSP)plane plane ECP - GSP
    4h 40m
    $282–793

  5. Fly Destin–Fort Walton Beach Airport to Asheville Regional Airport, drive

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Asheville Regional Airport (AVL)plane plane VPS - AVL
    2. Drive from Asheville-Airport-AVL to Spartanburgcar car
    4h 35m
    $107–405

  6. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Servicios Zapata - Spartanburgbus bus
    16h 57m
    $228–322

Destin–Fort Walton Beach Airport (VPS) to Greenville–Spartanburg International Airport (GSP) flights

Calendar62Weekly Planes
Duration4h 6mAverage Duration
Ticket$85Cheapest Price
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Comparing Your Travel Options

Map of how to get from Destin to Spartanburg.ExpandLaunch map view
  • Distance: 429.4 mi
  • Duration: 4h 2m

What companies run services between Destin, FL, USA and Spartanburg, SC, USA?

Delta, American Airlines, and Southwest Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Greenville–Spartanburg International Airport (GSP) every 3 hours.

Airlines
Bus operators
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