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How to get fromDestin to Winston-Salemby plane, taxi, bus, or car

Find Transport to Winston-Salem

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There are 8 ways to get from Destin to Winston-Salem by plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Destin–Fort Walton Beach Airport to Piedmont Triad International Airport

    best
    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Piedmont Triad International Airport (GSO)plane plane VPS - GSO
    4h 52m
    $182–823

  2. Drive  610.4 mi

    cheapest
    1. Drive from Destin to Winston-Salemcar car 610.4 mi
    12h 5m
    $112–161

  3. Taxi, bus

    1. Take the taxi from Destin to Crestviewtaxi taxi
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    18h 2m
    $226–322

  4. Taxi to Northwest Florida Beaches International Airport, fly to Piedmont Triad International Airport

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Piedmont Triad International Airport (GSO)plane plane ECP - GSO
    5h 38m
    $286–896

  5. Taxi to Pensacola International Airport, fly to Piedmont Triad International Airport

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Piedmont Triad International Airport (GSO)plane plane PNS - GSO
    5h 44m
    $257–875

  6. Fly Destin–Fort Walton Beach Airport to Charlotte Douglas International Airport, bus

    1. Fly from Destin–Fort Walton Beach Airport (VPS) to Charlotte Douglas International Airport (CLT)plane plane VPS - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    5h 21m
    $134–596

  7. Taxi to Northwest Florida Beaches International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the taxi from Destin to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Charlotte Douglas International Airport (CLT)plane plane ECP - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 1m
    $238–719

  8. Taxi to Pensacola International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the taxi from Destin to Pensacola-Airport-PNStaxi taxi
    2. Fly from Pensacola International Airport (PNS) to Charlotte Douglas International Airport (CLT)plane plane PNS - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 9m
    $214–668

Destin–Fort Walton Beach Airport (VPS) to Piedmont Triad International Airport (GSO) flights

Calendar70Weekly Planes
Duration4h 42mAverage Duration
Ticket$123Cheapest Price
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Comparing Your Travel Options

Map of how to get from Destin to Winston-Salem.ExpandLaunch map view
  • Distance: 582.8 mi
  • Duration: 4h 52m

What companies run services between Destin, FL, USA and Winston-Salem, NC, USA?

Delta and American Airlines fly from Destin–Fort Walton Beach Airport (VPS) to Piedmont Triad International Airport (GSO) every 3 hours.

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