There are 5 ways to get from Detroit Lakes Station to Mayo Clinic by train, bus, car, taxi, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Detroit Lakes Amtrak Station to St. Paul-Minneapolistrain Empire Builder
- Take the bus from St. Paul to Rochesterbus Jefferson Lines 965
6h 39m$92–172Drive 279.5 mi
cheapest- Drive from Detroit Lakes Station to Mayo Cliniccar 279.5 mi
5h 37m$51–74Bus
- Take the bus from Detroit Lakes to Brainerdbus
- Take the bus from Perkins Restaurant & Bakery - Brainerd to Minneapolis / St Paul Airportbus
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
9h 40m$142–154Taxi, fly to Rochester
- Take the taxi from Detroit Lakes Station to Fargo-Airport-FARtaxi
- Fly from Hector International Airport (FAR) to Rochester (RST)plane FAR - RST
5h 49m$173–699Taxi, fly to Minneapolis–Saint Paul International Airport, bus
- Take the taxi from Detroit Lakes Station to Fargo-Airport-FARtaxi
- Fly from Hector International Airport (FAR) to Minneapolis–Saint Paul International Airport (MSP)plane FAR - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
5h 2m$234–811
Detroit Lakes Station to Mayo Clinic by train, bus, and foot
Questions & Answers
The cheapest way to get from Detroit Lakes Station to Mayo Clinic is to drive which costs $50 - $75 and takes 5h 37m.
The fastest way to get from Detroit Lakes Station to Mayo Clinic is to taxi and fly and bus which takes 5h 2m and costs $230 - $850.
No, there is no direct bus from Detroit Lakes Station to Mayo Clinic. However, there are services departing from Detroit Lakes and arriving at Groome Transportation Office - Rochester via Perkins Restaurant & Bakery - Brainerd and Minneapolis / St Paul Airport. The journey, including transfers, takes approximately 9h 40m.
The distance between Detroit Lakes Station and Mayo Clinic is 280 miles. The road distance is 281.1 miles.
The best way to get from Detroit Lakes Station to Mayo Clinic without a car is to train and bus which takes 6h 39m and costs $90 - $180.
It takes approximately 6h 39m to get from Detroit Lakes Station to Mayo Clinic, including transfers.
Detroit Lakes Station to Mayo Clinic bus services, operated by Jefferson Lines, depart from Detroit Lakes station.
Detroit Lakes Station to Mayo Clinic bus services, operated by Jefferson Lines, arrive at Brainerd station.
Yes, the driving distance between Detroit Lakes Station to Mayo Clinic is 281 miles. It takes approximately 5h 37m to drive from Detroit Lakes Station to Mayo Clinic.
There are 68+ hotels available in Mayo Clinic.
What companies run services between Detroit Lakes Station, MN, USA and Mayo Clinic, MN, USA?
You can take a bus from Detroit Lakes to Mayo Clinic via Brainerd, Perkins Restaurant & Bakery - Brainerd, Minneapolis / St Paul Airport, and Groome Transportation Office - Rochester in around 9h 40m.
- Website
- delta.com
Flights from Hector International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $80–550
Flights from Hector International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $90–650
- Website
- aa.com
Flights from Hector International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $140–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Detroit Lakes Amtrak Station to St. Paul-Minneapolis
- Ave. Duration
- 4h 6m
- Frequency
- Twice daily
- Estimated price
- $60–140
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Bus from Detroit Lakes to Brainerd
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
- Phone
- +1 320-316-0943
- Website
- groometransportation.com
Bus from Perkins Restaurant & Bakery - Brainerd to Minneapolis / St Paul Airport
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- $60
- Schedules at
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
- Ave. Duration
- 1h
- Estimated price
- $90–110
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide







