There are 7 ways to get from Detroit to Big Pine Key by plane, bus, bus (Greyhound, Flixbus), train, shuttle, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Detroit to Key West International Airport, bus
best- Fly from Detroit (DTW) to Key West International Airport (EYW)plane DTW - EYW
- Take the bus from Key West Airport to Big Pine Keybus
8h 32m$116–559Bus
- Take the bus from Detroit Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
35h 30m$233–384Bus, train, shuttle
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the train from Toledo to Delray Beach Amtraktrain
- Take the train from Delray Beach Station to Miami Airport Stationtrain
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
2d 1h$621–1,326Drive 1,461.2 mi
- Drive from Detroit to Big Pine Keycar 1,461.2 mi
25h 35m$267–386Fly Detroit to Miami International Airport, shuttle
- Fly from Detroit (DTW) to Miami International Airport (MIA)plane DTW - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 3m$312–782Fly Detroit to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Detroit (DTW) to Fort Lauderdale–Hollywood International Airport (FLL)plane DTW - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
9h 26m$332–1,202Bus to Cleveland-Hopkins International Airport, fly to Miami International Airport, shuttle
- Take the bus from Detroit Bus Station to Cleveland Bus Stationbus
- Fly from Cleveland-Hopkins International Airport (CLE) to Miami International Airport (MIA)plane CLE - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
11h 22m$298–1,022
Detroit to Big Pine Key by bus
Comparing Your Travel Options
The cheapest way to get from Detroit to Big Pine Key is to bus which costs $230 - $390 and takes 35h 30m.
The fastest way to get from Detroit to Big Pine Key is to fly and bus which takes 8h 32m and costs $110 - $600.
No, there is no direct bus from Detroit station to Big Pine Key. However, there are services departing from Detroit Bus Station and arriving at Big Pine Key via Atlanta Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 35h 30m.
The distance between Detroit and Big Pine Key is 1280 miles. The road distance is 1469.8 miles.
The best way to get from Detroit to Big Pine Key without a car is to bus which takes 35h 30m and costs $230 - $390.
It takes approximately 8h 32m to get from Detroit to Big Pine Key, including transfers.
Detroit to Big Pine Key bus services, operated by Greyhound USA, depart from Detroit Bus Station.
Detroit to Big Pine Key bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Detroit to Big Pine Key is 1470 miles. It takes approximately 25h 35m to drive from Detroit to Big Pine Key.
Book your Detroit to Big Pine Key bus tickets online with Omio and FlixBus.
What companies run services between Detroit, MI, USA and Big Pine Key, FL, USA?
You can take a bus from Detroit Bus Station to Big Pine Key via Atlanta Bus Station and Miami Airport Station in around 35h 30m.
- Website
- delta.com
Flights from Detroit to Key West International Airport via Atlanta
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $110–550
Flights from Detroit to Miami International Airport
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- $140–700
Flights from Detroit to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- $140–700
Flights from Cleveland-Hopkins International Airport to Miami International Airport via Atlanta
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $130–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Delray Beach Amtrak
- Ave. Duration
- 41h 4m
- Frequency
- Once daily
- Estimated price
- $460–1,100
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Key West Airport to Big Pine Key
- Ave. Duration
- 40 min
- Frequency
- 3 times a day
- Estimated price
- $4–7
- Website
- Greyhound
Bus from Detroit Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 20m
- Frequency
- Twice daily
- Estimated price
- $110–180
- Website
- Greyhound
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $100–170
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $19–35
- Website
- Greyhound
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Detroit Bus Station to Cleveland Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $24–40
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
There are 112+ hotels available in Big Pine Key.





