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How to get fromDetroit to Biloxiby plane, bus (Greyhound), train (Amtrak), car, bus, or train

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There are 6 ways to get from Detroit to Biloxi by plane, bus (Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Detroit to Gulfport-Biloxi Regional Airport

    best
    1. Fly from Detroit (DTW) to Gulfport-Biloxi Regional Airport (GPT)plane plane DTW - GPT
    6h 59m
    $167–697

  2. Bus (Greyhound)

    1. Take the bus from Detroit Bus Station to Montgomery Intermodal Centerbus bus Greyhound US0112
    2. Take the bus from Montgomery Intermodal Center to Biloxi Transit Centerbus bus Greyhound US0602
    25h
    $181–342

  3. Train (Amtrak)

    1. Take the train from Detroit to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    28h 11m
    $417–888

  4. Drive 1,023.7 mi

    1. Drive from Detroit to Biloxicar car 1,023.7 mi
    17h 5m
    $187–270

  5. Bus to Cleveland-Hopkins International Airport, fly to Gulfport-Biloxi Regional Airport

    1. Take the bus from Detroit Bus Station to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Gulfport-Biloxi Regional Airport (GPT)plane plane CLE - GPT
    9h
    $194–746

  6. Fly Detroit to Louis Armstrong New Orleans International Airport, train

    1. Fly from Detroit (DTW) to Louis Armstrong New Orleans International Airport (MSY)plane plane DTW - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    8h 18m
    $470–1,162

Detroit to Biloxi by bus (Greyhound)

Calendar7Weekly Buses
Duration25hAverage Duration
Ticket$181Cheapest Price
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Questions & Answers

Map of how to get from Detroit to Biloxi.ExpandLaunch map view
  • Distance: 909.7 mi
  • Duration: 6h 59m

What companies run services between Detroit, MI, USA and Biloxi, MS, USA?

Delta, American Airlines, and United Airlines fly from Detroit (DTW) to Gulfport-Biloxi Regional Airport (GPT) every 2 hours. Alternatively, you can take a bus from Detroit Bus Station to Biloxi Transit Center via Montgomery Intermodal Center in around 25h.

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