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How to get fromDetroit to Florida Keysby plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

Find Transport to Florida Keys

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There are 8 ways to get from Detroit to Florida Keys by plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Detroit to Key West International Airport

    best
    1. Fly from Detroit (DTW) to Key West International Airport (EYW)plane plane DTW - EYW
    9h 30m
    $199–696

  2. Bus

    1. Take the bus from Detroit Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    37h
    $255–422

  3. Bus, train

    1. Take the bus from Detroit Bus Station to Toledo Bus Stopbus bus
    2. Take the train from Toledo to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 2h
    $1,049–1,700

  4. Drive  1,474.9 mi

    1. Drive from Detroit to Florida Keyscar car 1,474.9 mi
    25h 56m
    $270–389

  5. Fly Detroit to Miami International Airport, shuttle

    1. Fly from Detroit (DTW) to Miami International Airport (MIA)plane plane DTW - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 28m
    $314–686

  6. Fly Detroit to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Detroit (DTW) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane DTW - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 54m
    $354–1,206

  7. Bus to Cleveland-Hopkins International Airport, fly to Key West International Airport

    1. Take the bus from Detroit Bus Station to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Key West International Airport (EYW)plane plane CLE - EYW
    12h 7m
    $209–629

  8. Bus to Cleveland-Hopkins International Airport, fly to Miami International Airport, shuttle

    1. Take the bus from Detroit Bus Station to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Miami International Airport (MIA)plane plane CLE - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    12h 53m
    $364–979

Detroit to Florida Keys by bus and foot

Calendar14Weekly Services
Duration37hAverage Duration
Ticket$255Cheapest Price
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Comparing Your Travel Options

Map of how to get from Detroit to Florida Keys.ExpandLaunch map view
  • Distance: 1,266.1 mi
  • Duration: 9h 30m

What companies run services between Detroit, MI, USA and Florida Keys, FL, USA?

Delta, Frontier Airlines, and Breeze Airways fly from Detroit (DTW) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Detroit Bus Station to Florida Keys via Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 37h.

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