There are 10 ways to get from Detroit to Greenville by plane, car, train, bus, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Bill And Hillary Clinton National Airport, drive
best- Fly from Detroit (DTW) to Bill And Hillary Clinton National Airport (LIT)plane DTW - LIT
- Drive from Bill And Hillary Clinton National Airport (LIT) to Greenvillecar
8h 24m$128–542Train, drive (Amtrak)
- Take the train from Detroit to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Greenwood Amtrak Stationtrain
- Drive from Greenwood Amtrak Station to Greenvillecar
20h 35m$297–629Bus, train, drive via Atlanta
- Take the bus from Detroit Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Jacksonbus
- Take the train from Jackson to Yazoo City Amtrak Stationtrain
- Drive from Yazoo City Amtrak Station to Greenvillecar
28h 23m$191–366Drive 854.3 mi
- Drive from Detroit to Greenvillecar 854.3 mi
16h 6m$156–226Fly to Monroe Regional Airport, taxi
- Fly from Detroit (DTW) to Monroe Regional Airport (MLU)plane DTW - MLU
- Take the taxi from Monroe Regional Airport (MLU) to Greenvilletaxi
9h 12m$144–628Fly to Jackson/Vicksburg, train, drive
- Fly from Detroit (DTW) to Jackson/Vicksburg (JAN)plane DTW - JAN
- Take the train from Jackson to Yazoo City Amtrak Stationtrain
- Drive from Yazoo City Amtrak Station to Greenvillecar
9h 36m$169–602Fly to Greenville International Airport
- Fly from Detroit (DTW) to Greenville International Airport (GLH)plane DTW - GLH
7h 12m$134–578Fly to Birmingham–Shuttlesworth International Airport, drive
- Fly from Detroit (DTW) to Birmingham–Shuttlesworth International Airport (BHM)plane DTW - BHM
- Drive from Birmingham-Airport-BHM to Greenvillecar
9h$192–877Fly to Huntsville International Airport-Carl T Jones Field, drive
- Fly from Detroit (DTW) to Huntsville International Airport-Carl T Jones Field (HSV)plane DTW - HSV
- Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Greenvillecar
9h 50m$157–687Bus, train, drive (Amtrak)
- Take the bus from Detroit to Chicago Union Stationbus
- Take the train from Chicago Union Station to Greenwood Amtrak Stationtrain
- Drive from Greenwood Amtrak Station to Greenvillecar
22h 12m$306–586
Detroit (DTW) to Bill And Hillary Clinton National Airport (LIT) flights
Questions & Answers
The cheapest way to get from Detroit to Greenville is to drive which costs $150 - $230 and takes 16h 6m.
The fastest way to get from Detroit to Greenville is to fly which takes 7h 12m and costs $130 - $600.
The distance between Detroit and Greenville is 879 miles. The road distance is 859.3 miles.
It takes approximately 8h 24m to get from Detroit to Greenville, including transfers.
Greenville is 1h behind Detroit. It is currently 6:34 AM in Detroit and 5:34 AM in Greenville.
Yes, the driving distance between Detroit to Greenville is 859 miles. It takes approximately 16h 6m to drive from Detroit to Greenville.
There are 10+ hotels available in Greenville.
What companies run services between Detroit, MI, USA and Greenville, MS, USA?
Delta and Key Lime fly from Detroit (DTW) to Greenville International Airport (GLH) 5 times a day.
- Website
- delta.com
Flights from Detroit to Bill And Hillary Clinton National Airport via Atlanta
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $120–600
Flights from Detroit to Monroe Regional Airport via Atlanta
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $120–600
Flights from Detroit to Monroe Regional Airport via Nashville, Atlanta
- Ave. Duration
- 8h 18m
- When
- Every day
- Estimated price
- $120–600
Flights from Detroit to Monroe Regional Airport via Greenville/Spartanburg, Atlanta
- Ave. Duration
- 7h 55m
- When
- Saturday
- Estimated price
- $120–600
Flights from Detroit to Monroe Regional Airport via Covington, Atlanta
- Ave. Duration
- 9h 17m
- When
- Every day
- Estimated price
- $120–600
Flights from Detroit to Monroe Regional Airport via Knoxville, Atlanta
- Ave. Duration
- 9h 30m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $120–600
Flights from Detroit to Monroe Regional Airport via Columbus, Atlanta
- Ave. Duration
- 9h 30m
- When
- Every day
- Estimated price
- $120–600
Flights from Detroit to Jackson/Vicksburg via Atlanta
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $110–550
Flights from Detroit to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $140–800
Flights from Detroit to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $160–850
Flights from Detroit to Huntsville International Airport-Carl T Jones Field
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $100–600
Flights from Detroit to Huntsville International Airport-Carl T Jones Field via Atlanta
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $120–650
- Website
- aa.com
Flights from Detroit to Bill And Hillary Clinton National Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $140–650
Flights from Detroit to Bill And Hillary Clinton National Airport via Chicago O'Hare
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $100–500
Flights from Detroit to Bill And Hillary Clinton National Airport via Charlotte
- Ave. Duration
- 6h 18m
- When
- Every day
- Estimated price
- $130–600
Flights from Detroit to Monroe Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 10m
- When
- Every day
- Estimated price
- $140–650
Flights from Detroit to Jackson/Vicksburg via Charlotte
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $120–600
Flights from Detroit to Jackson/Vicksburg via Dallas/Ft.Worth
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $150–650
Flights from Detroit to Jackson/Vicksburg via Reagan Washington
- Ave. Duration
- 7h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–650
Flights from Detroit to Birmingham–Shuttlesworth International Airport via Charlotte
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $170–900
Flights from Detroit to Huntsville International Airport-Carl T Jones Field via Charlotte
- Ave. Duration
- 4h 35m
- When
- Sunday
- Estimated price
- $130–650
- Website
- united.com
Flights from Detroit to Bill And Hillary Clinton National Airport via Chicago O'Hare
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $100–500
Flights from Detroit to Bill And Hillary Clinton National Airport via Houston
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $150–700
Flights from Detroit to Jackson/Vicksburg via Houston
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $150–700
Flights from Detroit to Huntsville International Airport-Carl T Jones Field via Washington Dulles
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $140–700
- Website
- southwest.com
Flights from Detroit to Bill And Hillary Clinton National Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–500
Flights from Detroit to Jackson/Vicksburg via Nashville
- Ave. Duration
- 4h
- When
- Saturday
- Estimated price
- $100–500
Flights from Detroit to Birmingham–Shuttlesworth International Airport via Nashville
- Ave. Duration
- 3h 52m
- When
- Saturday, Tuesday, Wednesday, and Sunday
- Estimated price
- $140–800
Flights from Detroit to Birmingham–Shuttlesworth International Airport via Chicago Midway
- Ave. Duration
- 4h 15m
- When
- Saturday
- Estimated price
- $170–850
- Website
- keylimeair.com
Flights from Detroit to Greenville International Airport via Atlanta
- Ave. Duration
- 5h
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Detroit to Greenville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 15m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–650
Flights from Detroit to Greenville International Airport via Greenville/Spartanburg, Atlanta
- Ave. Duration
- 7h 10m
- When
- Saturday
- Estimated price
- $120–600
Flights from Detroit to Greenville International Airport via Knoxville, Atlanta
- Ave. Duration
- 8h 45m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Detroit to Greenville International Airport via Columbus, Atlanta
- Ave. Duration
- 8h 45m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Detroit to Greenville International Airport via Nashville, Atlanta
- Ave. Duration
- 8h 45m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–600
Flights from Detroit to Greenville International Airport via Covington, Atlanta
- Ave. Duration
- 8h 49m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $280–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Detroit to Chicago Union Station
- Ave. Duration
- 5h 6m
- Frequency
- 3 times a day
- Estimated price
- $85–190
- Website
- Amtrak
Train from Chicago Union Station to Greenwood Amtrak Station
- Ave. Duration
- 13h 25m
- Frequency
- Once daily
- Estimated price
- $200–430
- Website
- Amtrak
Train from Jackson to Yazoo City Amtrak Station
- Ave. Duration
- 56 min
- Frequency
- Once daily
- Estimated price
- $14–30
- Website
- Amtrak
Train from Jackson to Yazoo City Amtrak Station
- Ave. Duration
- 56 min
- Frequency
- Once daily
- Estimated price
- $14–30
- Website
- Amtrak
Train from Chicago Union Station to Greenwood Amtrak Station
- Ave. Duration
- 13h 25m
- Frequency
- Once daily
- Estimated price
- $200–430
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Detroit Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 20m
- Frequency
- 4 times a day
- Estimated price
- $100–210
- Website
- Greyhound
Bus from Atlanta Bus Station to Jackson
- Ave. Duration
- 7h 40m
- Frequency
- 4 times a day
- Estimated price
- $55–110
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Detroit to Chicago Union Station
- Ave. Duration
- 5h 27m
- Frequency
- Once a week
- Estimated price
- $95–140
- Website
- Amtrak
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide





