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How to get fromDetroit to Harrisburgby train, taxi, bus (Greyhound, Flixbus, Amtrak), car, plane, or bus (Flixbus)

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There are 6 ways to get from Detroit to Harrisburg by train, taxi, bus (Greyhound, Flixbus, Amtrak), car, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, taxi

    best
    1. Take the train from Detroit to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carbondaletrain train
    3. Take the taxi from Carbondale to Harrisburgtaxi taxi
    12h 26m
    $269–504

  2. Bus

    cheapest
    1. Take the bus from Detroit, MI to Indianapolis, INbus bus
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    16h 39m
    $87–202

  3. Drive 499.4 mi

    1. Drive from Detroit to Harrisburgcar car 499.4 mi
    9h 4m
    $92–132

  4. Fly to Evansville, drive

    1. Fly from Detroit (DTW) to Evansville (EVV)plane plane DTW - EVV
    2. Drive from Evansville (EVV) to Harrisburgcar car
    7h 27m
    $89–451

  5. Bus via Milwaukee

    1. Take the bus from Detroit Bus Station to Milwaukee Intermodal Stationbus bus FlixBus 2550
    2. Take the bus from Water & Chicago - Circle K to Marathon Gas Station - Marionbus bus Milwaukee
    18h 17m
    $150–303

  6. Fly to Williamson County Regional Airport

    1. Fly from Detroit (DTW) to Williamson County Regional Airport (MWA)plane plane DTW - MWA
    8h 10m
    $93–444

Detroit (DTW) to Evansville (EVV) flights

Calendar70Weekly Planes
Duration5h 37mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Detroit to Harrisburg.ExpandLaunch map view
  • Distance: 627.2 mi
  • Duration: 12h 26m

What companies run services between Detroit, MI, USA and Harrisburg, IL, USA?

You can take a bus from Detroit, MI to Harrisburg, IL via Indianapolis Union Station, St Louis Bus Station, Carbondale,IL - Amtrak, RMTD Park and Ride return, and Marion, IL in around 16h 39m. Alternatively, American Airlines, United Airlines, and Corporate Flight Management Inc fly from Detroit (DTW) to Williamson County Regional Airport (MWA) 4 times a day.

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