There are 7 ways to get from Detroit to Key West (Island) by plane, bus (Greyhound, Flixbus), bus, train, shuttle, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Detroit
best- Fly from Detroit (DTW) to Key West International Airport (EYW)plane DTW - EYW
6h 52m$112–552Bus to Bishop International Airport, fly
cheapest- Take the bus from Detroit Bus Station to Flintbus
- Fly from Bishop International Airport (FNT) to Key West International Airport (EYW)plane FNT - EYW
7h 12m$99–424Bus
- Take the bus from Detroit Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key West Airportbus
36h 20m$238–390Bus, train, shuttle
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the train from Toledo to Hollywood Amtrak Stationtrain
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
2d 2h$649–1,343Drive 1,490.4 mi
- Drive from Detroit to Key Westcar 1,490.4 mi
26h 19m$272–393Bus to Toledo, fly
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Fly from Toledo (TOL) to Key West International Airport (EYW)plane TOL - EYW
17h 48m$126–482Bus to Cleveland-Hopkins International Airport, fly
- Take the bus from Detroit Bus Station to Cleveland Bus Stationbus
- Fly from Cleveland-Hopkins International Airport (CLE) to Key West International Airport (EYW)plane CLE - EYW
9h 16m$128–532
Detroit to Key West (Island) by bus
Comparing Your Travel Options
The cheapest way to get from Detroit to Key West (Island) is to bus and fly which costs $95 - $430 and takes 7h 12m.
The fastest way to get from Detroit to Key West (Island) is to fly which takes 6h 52m and costs $110 - $550.
No, there is no direct bus from Detroit station to Key West (Island). However, there are services departing from Detroit Bus Station and arriving at Key West Airport via Atlanta Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 36h 20m.
The distance between Detroit and Key West (Island) is 1252 miles. The road distance is 1499.1 miles.
The best way to get from Detroit to Key West (Island) without a car is to bus which takes 36h 20m and costs $230 - $390.
It takes approximately 6h 52m to get from Detroit to Key West (Island), including transfers.
Detroit to Key West (Island) bus services, operated by Greyhound USA, depart from Detroit Bus Station.
The best way to get from Detroit to Key West (Island) is to fly which takes 6h 52m and costs $110 - $550. Alternatively, you can bus, which costs $230 - $390 and takes 36h 20m.
Detroit to Key West (Island) bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Detroit to Key West (Island) is 1499 miles. It takes approximately 26h 19m to drive from Detroit to Key West (Island).
What companies run services between Detroit, MI, USA and Key West (Island), FL, USA?
Delta and American Airlines fly from Detroit (DTW) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Detroit Bus Station to Key West Airport via Atlanta Bus Station and Miami Airport Station in around 36h 20m.
- Website
- aa.com
Flights from Detroit to Key West International Airport via Charlotte
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $110–550
Flights from Toledo to Key West International Airport via Sarasota/Bradenton, Miami
- Ave. Duration
- 16h 11m
- When
- Friday
- Estimated price
- $90–410
Flights from Cleveland-Hopkins International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $100–490
Flights from Cleveland-Hopkins International Airport to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $110–550
Flights from Cleveland-Hopkins International Airport to Key West International Airport via Miami
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $100–500
Flights from Bishop International Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 9h 53m
- When
- Tuesday to Thursday
- Estimated price
- $100–450
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Hollywood Amtrak Station
- Ave. Duration
- 41h 57m
- Frequency
- Once daily
- Estimated price
- $470–1,100
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Detroit Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 20m
- Frequency
- Twice daily
- Estimated price
- $110–180
- Website
- Greyhound
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $100–170
- Website
- Greyhound
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $24–40
- Website
- Greyhound
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Detroit Bus Station to Cleveland Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $24–40
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Book your Detroit to Key West (Island) bus tickets online with Omio and FlixBus.
There are 969+ hotels available in Key West (Island).





