What is the cheapest way to get from Detroit to Knoxville?

The cheapest way to get from Detroit to Knoxville is to drive which costs $85 - $130 and takes 8h 35m.

What is the fastest way to get from Detroit to Knoxville?

The fastest way to get from Detroit to Knoxville is to fly which takes 3h 52m and costs $280 - $1,500.

Is there a direct bus between Detroit and Knoxville?

No, there is no direct bus from Detroit station to Knoxville. However, there are services departing from Detroit Bus Station and arriving at Knoxville via Toledo Bus Stop and New York. The journey, including transfers, takes approximately 27h 46m.

How far is it from Detroit to Knoxville?

The distance between Detroit and Knoxville is 481 miles. The road distance is 510.8 miles.

How do I travel from Detroit to Knoxville without a car?

The best way to get from Detroit to Knoxville without a car is to bus via Toledo which takes 27h 46m and costs $280 - $450.

How long does it take to get from Detroit to Knoxville?

It takes approximately 3h 52m to get from Detroit to Knoxville, including transfers.

Where do I catch the Detroit to Knoxville bus from?

Detroit to Knoxville bus services, operated by Greyhound USA, depart from Detroit Bus Station.

Bus or fly from Detroit to Knoxville?

The best way to get from Detroit to Knoxville is to fly which takes 3h 52m and costs $280 - $1,500. Alternatively, you can bus via Toledo, which costs $280 - $450 and takes 27h 46m.

Where does the Detroit to Knoxville bus arrive?

Detroit to Knoxville bus services, operated by Greyhound USA, arrive at Toledo Bus Stop station.

Can I drive from Detroit to Knoxville?

Yes, the driving distance between Detroit to Knoxville is 511 miles. It takes approximately 8h 35m to drive from Detroit to Knoxville.

Where can I stay near Knoxville?

There are 320+ hotels available in Knoxville.

Detroit to Knoxville - 8 ways to travel via train, plane, bus, and car

There are 8 ways to get from Detroit to Knoxville by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Mcghee Tyson Airport
best
1. Fly from Detroit (DTW) to Mcghee Tyson Airport (TYS)plane DTW - TYS
3h 52m
$287–1,472
Drive 507.9 mi
cheapest
1. Drive from Detroit to Knoxvillecar 507.9 mi
8h 35m
$90–130
Bus via Toledo
1. Take the bus from Detroit Bus Station to Toledo Bus Stopbus
2. Take the bus from Toledo Bus Stop to New York Midtownbus
3. Take the bus from New York to Knoxvillebus Nyc
27h 46m
$289–450
Train, bus
1. Take the train from Windsor to Aldershottrain
2. Take the train from Aldershot to New York Penn Stationtrain
3. Take the bus from New York, NY to Knoxville, TNbus Ny
30h 27m
$319–674
Fly to Chattanooga Metropolitan Airport, drive
1. Fly from Detroit (DTW) to Chattanooga Metropolitan Airport (CHA)plane DTW - CHA
2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar
5h 28m
$115–579
Bus, train via Farragut
1. Take the bus from Detroit Bus Station to Toledo Bus Stopbus
2. Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain
3. Take the bus from New York to Knoxvillebus Nyc
30h 49m
$589–940
Bus
1. Take the bus from Detroit Bus Station to Port Authority Bus Terminalbus Greyhound US0420
2. Take the bus from New York to Knoxvillebus Nyc
30h 52m
$316–449
Bus, train
1. Take the bus from Detroit Bus Station to Toledo Bus Stopbus
2. Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain
3. Take the bus from New York, NY to Knoxville, TNbus Ny
30h 53m
$544–850

Detroit (DTW) to Mcghee Tyson Airport (TYS) flights

43Weekly Planes

3h 24mAverage Duration

$233Cheapest Price

See schedules

Comparing Your Travel Options

Map of how to get from Detroit to Knoxville.

Launch map view

Distance: 478.1 mi
Duration: 3h 52m

What companies run services between Detroit, MI, USA and Knoxville, TN, USA?

Delta, United Airlines, and American Airlines fly from Detroit (DTW) to Mcghee Tyson Airport (TYS) every 4 hours. Alternatively, you can take a bus from Detroit Bus Station to Knoxville via Toledo Bus Stop, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 27h 46m.

Airlines

Train operators

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.