Rome2Rio

How to get fromDetroit to La Crosseby plane, train (Amtrak), bus (Flixbus), car, bus, train, or bus (Amtrak)

Find Transport to La Crosse

See all options

There are 8 ways to get from Detroit to La Crosse by plane, train (Amtrak), bus (Flixbus), car, bus, train, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to La Crosse

    best
    1. Fly from Detroit (DTW) to La Crosse (LSE)plane plane DTW - LSE
    6h 31m
    $91–425

  2. Train (Amtrak)

    1. Take the train from Detroit to Chicago Union Stationtrain train Wolverine
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    11h 5m
    $182–375

  3. Bus

    1. Take the bus from Detroit Bus Station to Milwaukee Intermodal Stationbus bus FlixBus 2550
    2. Take the bus from Milwaukee to La Crossebus bus Jefferson 966 / ...
    12h 20m
    $117–182

  4. Drive 562.5 mi

    1. Drive from Detroit to La Crossecar car 562.5 mi
    9h 20m
    $103–149

  5. Fly to Dane County Regional Airport-Truax Field, bus

    1. Fly from Detroit (DTW) to Dane County Regional Airport-Truax Field (MSN)plane plane DTW - MSN
    2. Take the bus from Madison to UW La Crossebus bus
    8h 4m
    $126–611

  6. Fly to Minneapolis–Saint Paul International Airport, train

    1. Fly from Detroit (DTW) to Minneapolis–Saint Paul International Airport (MSP)plane plane DTW - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    8h 14m
    $514–1,290

  7. Fly to Appleton International Airport, bus

    1. Fly from Detroit (DTW) to Appleton International Airport (ATW)plane plane DTW - ATW
    2. Take the bus from Appleton Valley Transit to La Crosse Grand River Stationbus bus
    8h 48m
    $162–760

  8. Bus via Chicago

    1. Take the bus from Detroit to Chicago Union Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to La Crossebus bus
    14h 19m
    $156–252

Detroit to La Crosse by train (Amtrak)

Calendar21Weekly Trains
Duration11h 5mAverage Duration
Ticket$182Cheapest Price
See schedules

Questions & Answers

Map of how to get from Detroit to La Crosse.ExpandLaunch map view
  • Distance: 444.6 mi
  • Duration: 6h 31m

What companies run services between Detroit, MI, USA and La Crosse, WI, USA?

American Airlines, United Airlines, and Delta fly from Detroit (DTW) to La Crosse (LSE) every 4 hours. Alternatively, you can take a train from Detroit to La Crosse Amtrak Station via Chicago Union Station in around 11h 5m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers