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How to get fromDetroit to Lisleby train (Amtrak), bus (Greyhound, Flixbus), car, plane, train, bus (Amtrak), or bus

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There are 10 ways to get from Detroit to Lisle by train (Amtrak), bus (Greyhound, Flixbus), car, plane, train, bus (Amtrak), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Detroit to Chicago Union Stationtrain train Wolverine
    6h 24m
    $96–191

  2. Bus

    cheapest
    1. Take the bus from Detroit Bus Station to Chicago Bus Stationbus bus Greyhound US0160
    7h 32m
    $49–91

  3. Drive 299.5 mi

    1. Drive from Detroit to Lislecar car 299.5 mi
    5h 8m
    $55–79

  4. Fly Detroit to Chicago Midway International Airport, train

    1. Fly from Detroit (DTW) to Chicago Midway International Airport (MDW)plane plane DTW - MDW
    2. Take the train from Chicago Union Station to Lisletrain train
    5h 16m
    $138–473

  5. Bus via North Riverside Park Mall (Amtrak)

    1. Take the bus from Detroit to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    9h 46m
    $106–152

  6. Fly Detroit to Chicago O'Hare International Airport, train

    1. Fly from Detroit (DTW) to Chicago O'Hare International Airport (ORD)plane plane DTW - ORD
    2. Take the train from Chicago Union Station to Lisletrain train
    5h 37m
    $158–663

  7. Drive to Capital Region International Airport, fly to Chicago O'Hare International Airport

    1. Drive from Detroit to Lansing-Airport-LANcar car
    2. Fly from Capital Region International Airport (LAN) to Chicago O'Hare International Airport (ORD)plane plane LAN - ORD
    5h 13m
    $63–325

  8. Bus to Bishop International Airport, fly to Chicago O'Hare International Airport, train

    1. Take the bus from Detroit Bus Station to Flintbus bus
    2. Fly from Bishop International Airport (FNT) to Chicago O'Hare International Airport (ORD)plane plane FNT - ORD
    3. Take the train from Chicago Union Station to Lisletrain train
    6h 22m
    $51–257

  9. Fly Detroit to South Bend, train

    1. Fly from Detroit (DTW) to South Bend (SBN)plane plane DTW - SBN
    2. Take the train from South Bend Airport to Van Buren St.train train
    7h 34m
    $92–576

  10. Fly Detroit to General Mitchell International Airport, train

    1. Fly from Detroit (DTW) to General Mitchell International Airport (MKE)plane plane DTW - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Lisletrain train
    7h 31m
    $635–1,082

Detroit to Lisle by train (Amtrak)

Calendar21Weekly Trains
Duration6h 24mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

Map of how to get from Detroit to Lisle.ExpandLaunch map view
  • Distance: 304.5 mi
  • Duration: 6h 24m

What companies run services between Detroit, MI, USA and Lisle, IL, USA?

Amtrak operates a train from Detroit to Chicago Union Station 3 times a day. Tickets cost $90–190 and the journey takes 5h 6m. Alternatively, Greyhound USA operates a bus from Detroit Bus Station to Chicago Bus Station 3 times a day. Tickets cost $45–85 and the journey takes 6h 5m. Flixbus USA also services this route twice daily.

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