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How to get fromDetroit to Louisvilleby bus (Greyhound), car, plane, or bus

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There are 6 ways to get from Detroit to Louisville by bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Detroit Bus Station to Louisville Bus Stationbus bus Greyhound US0135 / ...
    7h 25m
    $85–120
  2. Bus via Columbus

    cheapest
    1. Take the bus from Detroit Bus Station to N Wilson Rd & Ferrell Pl - Columbusbus bus Detroit
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus bus Cleveland
    8h 50m
    $38–151
  3. Drive 356 mi

    1. Drive from Detroit to Louisvillecar car 356 mi
    6h 5m
    $65–94
  4. Fly to Louisville International Airport

    1. Fly from Detroit (DTW) to Louisville International Airport (SDF)plane plane DTW - SDF
    4h 33m
    $83–555
  5. Fly to Blue Grass Airport, drive

    1. Fly from Detroit (DTW) to Blue Grass Airport (LEX)plane plane DTW - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 38m
    $135–821
  6. Fly to Covington, bus

    1. Fly from Detroit (DTW) to Covington (CVG)plane plane DTW - CVG
    2. Take the bus from Cincinnati to Louisvillebus bus
    6h 58m
    $913–1,354

Detroit to Louisville by bus

Calendar21Weekly Buses
Duration7h 25mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

What companies run services between Detroit, MI, USA and Louisville, KY, USA?

Greyhound USA operates a bus from Detroit Bus Station to Louisville Bus Station twice daily. Tickets cost $55–110 and the journey takes 7h 25m. Jefferson Lines also services this route once daily. Alternatively, Delta and Southwest Airlines fly from Detroit (DTW) to Louisville International Airport (SDF) 4 times a day.

Airlines
Bus operators

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