There are 7 ways to get from Detroit to Mississippi by plane, train (Amtrak), bus (Amtrak, Greyhound, Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Memphis
best- Fly from Detroit (DTW) to Memphis (MEM)plane DTW - MEM
4h$184–979Fly to Gulfport-Biloxi Regional Airport
cheapest- Fly from Detroit (DTW) to Gulfport-Biloxi Regional Airport (GPT)plane DTW - GPT
6h 30m$143–716Train (Amtrak)
- Take the train from Detroit to Chicago Union Stationtrain Wolverine
- Take the train from Chicago Union Station to Jacksontrain City of New Orleans
21h 41m$262–589Bus
- Take the bus from Detroit to Chicago Union Stationbus
- Take the bus from Chicago Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Jacksonbus
22h 22m$182–306Drive 916.3 mi
- Drive from Detroit to Jacksoncar 916.3 mi
16h 15m$168–242Fly to Birmingham–Shuttlesworth International Airport, drive
- Fly from Detroit (DTW) to Birmingham–Shuttlesworth International Airport (BHM)plane DTW - BHM
- Drive from Birmingham-Airport-BHM to Tupelocar
6h 10m$206–1,042Bus, train
- Take the bus from Detroit Bus Station to Chicagobus FlixBus 2552
- Take the train from Homewood to Jacksontrain City of New Orleans
24h 27m$232–499
Detroit to Mississippi by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Detroit to Mississippi is to drive which costs $160 - $250 and takes 16h 15m.
The fastest way to get from Detroit to Mississippi is to fly which takes 4h and costs $180 - $1,000.
No, there is no direct bus from Detroit to Mississippi. However, there are services departing from Woodward & Gratiot and arriving at Jackson via Detroit, Chicago Bus Station and Memphis Bus Station. The journey, including transfers, takes approximately 22h 22m.
No, there is no direct train from Detroit to Mississippi. However, there are services departing from Detroit and arriving at Jackson via Chicago Union Station. The journey, including transfers, takes approximately 21h 41m.
The distance between Detroit and Mississippi is 643 miles. The road distance is 921.7 miles.
The best way to get from Detroit to Mississippi without a car is to train which takes 21h 41m and costs $260 - $600.
It takes approximately 4h to get from Detroit to Mississippi, including transfers.
Detroit to Mississippi bus services, operated by Amtrak, depart from Detroit station.
Detroit to Mississippi train services, operated by Amtrak, depart from Detroit station.
The best way to get from Detroit to Mississippi is to fly which takes 4h and costs $180 - $1,000. Alternatively, you can train, which costs $260 - $600 and takes 21h 41m, you could also bus, which costs $180 - $310 and takes 22h 22m.
What companies run services between Detroit, MI, USA and Mississippi, USA?
Delta and Southwest Airlines fly from Detroit (DTW) to Memphis (MEM) every 2 hours. Alternatively, you can take a train from Detroit to Jackson via Chicago Union Station in around 21h 41m.
- Website
- delta.com
Flights from Detroit to Memphis
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $160–950
Flights from Detroit to Memphis via Atlanta
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Detroit to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $130–700
Flights from Detroit to Gulfport-Biloxi Regional Airport via Columbus, Atlanta
- Ave. Duration
- 5h 56m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Detroit to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Detroit to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $190–1,100
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Detroit to Chicago Union Station
- Ave. Duration
- 5h 6m
- Frequency
- 3 times a day
- Estimated price
- $70–160
- Website
- Amtrak
Train from Chicago Union Station to Jackson
- Ave. Duration
- 15h 35m
- Frequency
- Once daily
- Estimated price
- $190–430
- Website
- Amtrak
Train from Homewood to Jackson
- Ave. Duration
- 14h 46m
- Frequency
- Once daily
- Estimated price
- $180–420
- Website
- Amtrak
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Detroit to Chicago Union Station
- Ave. Duration
- 5h 27m
- Frequency
- Once a week
- Estimated price
- $70–110
- Website
- Amtrak
Want to know more about travelling around United States
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Booking & Getting There
Detroit to Mississippi bus services, operated by Amtrak, arrive at Chicago Union Station.
Mississippi is 1h behind Detroit. It is currently 3:49 PM in Detroit and 2:49 PM in Mississippi.
Detroit to Mississippi train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Detroit to Mississippi is 922 miles. It takes approximately 16h 15m to drive from Detroit to Mississippi.
Book your Detroit to Mississippi train tickets online with Omio.
There are 221+ hotels available in Mississippi.



