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How to get fromDetroit to Orangeburgby plane, taxi, bus, train, car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Detroit to Orangeburg by plane, taxi, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Columbia, taxi

    best
    1. Fly from Detroit (DTW) to Columbia (CAE)plane plane DTW - CAE
    2. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    6h 27m
    $322–1,252

  2. Drive 741.3 mi

    cheapest
    1. Drive from Detroit to Orangeburgcar car 741.3 mi
    13h 17m
    $136–196

  3. Bus via Columbus

    1. Take the bus from Detroit Bus Station to N Wilson Rd & Ferrell Pl - Columbusbus bus
    2. Take the bus from Columbus to Charlottebus bus
    3. Take the bus from Charlotte to Orangeburgbus bus
    18h 58m

  4. Bus, train

    1. Take the bus from Detroit Bus Station to Toledo Bus Stopbus bus Greyhound US0420 / ...
    2. Take the train from Toledo to Denmark Amtrak Stationtrain train Floridian
    28h 18m
    $421–867

  5. Fly to Savannah, bus

    1. Fly from Detroit (DTW) to Savannah (SAV)plane plane DTW - SAV
    2. Take the bus from Savannah Bus Station to Orangeburgbus bus
    7h 32m
    $188–752

  6. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Detroit (DTW) to Charlotte Douglas International Airport (CLT)plane plane DTW - CLT
    2. Take the bus from Charlotte to Orangeburgbus bus
    8h 25m

  7. Bus

    1. Take the bus from Detroit Bus Station to Charlotte Bus Stationbus bus Greyhound US0140
    2. Take the bus from Charlotte Bus Station to Orangeburgbus bus Greyhound US0644S / ...
    20h 43m
    $144–267

Detroit (DTW) to Columbia (CAE) flights

Calendar127Weekly Planes
Duration4h 58mAverage Duration
Ticket$202Cheapest Price
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Questions & Answers

Map of how to get from Detroit to Orangeburg.ExpandLaunch map view
  • Distance: 644.6 mi
  • Duration: 6h 27m

What companies run services between Detroit, MI, USA and Orangeburg, SC, USA?

You can take a bus from Detroit Bus Station to Orangeburg via Columbus, Charlotte, and Orangeburg in around 18h 58m.

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