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How to get fromDetroit to Palo Altoby plane, bus (Greyhound, Flixbus), train, subway, car, or bus

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There are 7 ways to get from Detroit to Palo Alto by plane, bus (Greyhound, Flixbus), train, subway, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Detroit to San Francisco International Airport

    best
    1. Fly from Detroit (DTW) to San Francisco International Airport (SFO)plane plane DTW - SFO
    7h 50m
    $145–570

  2. Bus

    1. Take the bus from Detroit, MI to Indianapolis, INbus bus
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indio Bus Stationbus bus
    4. Take the bus from Indio Bus Station to Los Angeles Downtownbus bus
    5. Take the bus from Los Angeles, CA - Chinatown Station to San Jose, CA - Huong Lan Sandwichbus bus
    2d 11h
    $409–794

  3. Train, BART

    1. Take the train from Detroit to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Richmondtrain train
    3. Take the subway from Richmond to Millbraesubway subway
    2d 13h
    $859–1,807

  4. Drive 2,416.2 mi

    1. Drive from Detroit to Palo Altocar car 2,416.2 mi
    37h 49m
    $441–637

  5. Fly Detroit to Norman Y. Mineta San José International Airport

    1. Fly from Detroit (DTW) to Norman Y. Mineta San José International Airport (SJC)plane plane DTW - SJC
    9h 37m
    $219–711

  6. Fly Detroit to Oakland International Airport, train

    1. Fly from Detroit (DTW) to Oakland International Airport (OAK)plane plane DTW - OAK
    2. Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain train
    11h 10m
    $250–986

  7. Bus to Cleveland-Hopkins International Airport, fly to San Francisco International Airport

    1. Take the bus from Detroit Bus Station to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to San Francisco International Airport (SFO)plane plane CLE - SFO
    10h 45m
    $231–389

Detroit to Palo Alto by bus and foot

Calendar7Weekly Services
Duration2d 11hAverage Duration
Ticket$409Cheapest Price
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Questions & Answers

Map of how to get from Detroit to Palo Alto.ExpandLaunch map view
  • Distance: 2,116.3 mi
  • Duration: 7h 50m

What companies run services between Detroit, MI, USA and Palo Alto, CA, USA?

Delta, United Airlines, and two other airlines fly from Detroit (DTW) to San Francisco International Airport (SFO) every 2 hours. Alternatively, you can take a bus from Detroit, MI to El Camino & Churchill via Indianapolis Union Station, St Louis Bus Station, Indio Bus Station, Los Angeles Downtown, Los Angeles, CA - Chinatown Station, San Jose, CA - Huong Lan Sandwich, and King & Tully in around 2d 11h.

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