There are 7 ways to get from Detroit to Palo Alto by plane, bus (Greyhound), train, subway, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Detroit to San Francisco International Airport
best- Fly from Detroit (DTW) to San Francisco International Airport (SFO)plane DTW - SFO
8h 6m$175–480Bus
- Take the bus from Detroit to Indianapolisbus
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
- Take the bus from Los Angeles, CA - Chinatown Station to San Jose, CA - Huong Lan Sandwichbus
2d 12h$456–751Train, BART
- Take the train from Detroit to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Richmondtrain
- Take the subway from Richmond to Millbraesubway
2d 13h$1,471–2,360Drive 2,416.1 mi
- Drive from Detroit to Palo Altocar 2,416.1 mi
37h 49m$413–597Fly Detroit to Norman Y. Mineta San José International Airport
- Fly from Detroit (DTW) to Norman Y. Mineta San José International Airport (SJC)plane DTW - SJC
9h 35m$279–711Bus to Cleveland-Hopkins International Airport, fly to San Francisco International Airport
- Take the bus from Detroit Bus Station to Cleveland Bus Stationbus
- Fly from Cleveland-Hopkins International Airport (CLE) to San Francisco International Airport (SFO)plane CLE - SFO
10h 58m$185–713Fly Detroit to Oakland International Airport, train
- Fly from Detroit (DTW) to Oakland International Airport (OAK)plane DTW - OAK
- Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain
11h 20m$238–646
Detroit to Palo Alto by bus and tram
Comparing Your Travel Options
The cheapest way to get from Detroit to Palo Alto is to fly which costs $170 - $480 and takes 8h 6m.
The fastest way to get from Detroit to Palo Alto is to fly which takes 8h 6m and costs $170 - $480.
No, there is no direct bus from Detroit to Palo Alto. However, there are services departing from Detroit and arriving at El Camino & Churchill via Indianapolis Union Station, St Louis Bus Station, Los Angeles, CA - Chinatown Station and King & Tully. The journey, including transfers, takes approximately 2 days 12h.
No, there is no direct train from Detroit to Palo Alto. However, there are services departing from Detroit and arriving at California Avenue Caltrain Southbound via Chicago Union Station, Richmond and Millbrae Caltrain Southbound. The journey, including transfers, takes approximately 2 days 13h.
The distance between Detroit and Palo Alto is 2129 miles. The road distance is 2430.2 miles.
The best way to get from Detroit to Palo Alto without a car is to bus which takes 2 days 12h and costs $450 - $750.
It takes approximately 8h 6m to get from Detroit to Palo Alto, including transfers.
Detroit to Palo Alto bus services, operated by Barons Bus, depart from Detroit station.
Detroit to Palo Alto train services, operated by Amtrak, depart from Detroit station.
The best way to get from Detroit to Palo Alto is to fly which takes 8h 6m and costs $170 - $480. Alternatively, you can bus, which costs $450 - $750 and takes 2 days 12h.
What companies run services between Detroit, MI, USA and Palo Alto, CA, USA?
Delta, United Airlines, and two other airlines fly from Detroit (DTW) to San Francisco International Airport (SFO) hourly. Alternatively, you can take a bus from Detroit to El Camino & Churchill via Indianapolis Union Station, St Louis Bus Station, Los Angeles Union Station, Union Station - Metro A-Line, Chinatown Station, Los Angeles, CA - Chinatown Station, San Jose, CA - Huong Lan Sandwich, and King & Tully in around 2d 12h.
- Website
- delta.com
Flights from Detroit to San Francisco International Airport
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $150–700
Flights from Detroit to San Francisco International Airport via Salt Lake City
- Ave. Duration
- 7h 8m
- When
- Every day
- Estimated price
- $150–700
Flights from Detroit to San Francisco International Airport via Minneapolis
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $160–700
Flights from Detroit to Norman Y. Mineta San José International Airport via Salt Lake City
- Ave. Duration
- 7h 7m
- When
- Every day
- Estimated price
- $220–950
Flights from Detroit to Norman Y. Mineta San José International Airport via Minneapolis
- Ave. Duration
- 7h 17m
- When
- Every day
- Estimated price
- $220–1,000
Flights from Detroit to Norman Y. Mineta San José International Airport via Las Vegas
- Ave. Duration
- 7h 32m
- When
- Sunday
- Estimated price
- $230–1,000
Flights from Detroit to Norman Y. Mineta San José International Airport via Los Angeles
- Ave. Duration
- 8h 18m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Cleveland-Hopkins International Airport to San Francisco International Airport via Minneapolis
- Ave. Duration
- 7h 14m
- When
- Saturday
- Estimated price
- $150–650
Flights from Cleveland-Hopkins International Airport to San Francisco International Airport via Detroit
- Ave. Duration
- 7h 38m
- When
- Every day
- Estimated price
- $150–650
Flights from Detroit to Oakland International Airport via Salt Lake City
- Ave. Duration
- 6h 59m
- When
- Every day
- Estimated price
- $190–850
- Website
- southwest.com
Flights from Detroit to San Francisco International Airport via Chicago Midway
- Ave. Duration
- 7h 17m
- When
- Monday to Wednesday
- Estimated price
- $150–700
Flights from Detroit to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $220–950
Flights from Detroit to Norman Y. Mineta San José International Airport via Las Vegas
- Ave. Duration
- 7h 12m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- $230–1,000
Flights from Detroit to Norman Y. Mineta San José International Airport via Chicago Midway
- Ave. Duration
- 7h 36m
- When
- Every day
- Estimated price
- $220–950
Flights from Cleveland-Hopkins International Airport to San Francisco International Airport via Chicago Midway
- Ave. Duration
- 7h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- $140–650
Flights from Cleveland-Hopkins International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 7h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–650
Flights from Detroit to Oakland International Airport via Denver
- Ave. Duration
- 7h 13m
- When
- Every day
- Estimated price
- $200–850
Flights from Detroit to Oakland International Airport via Chicago Midway
- Ave. Duration
- 7h 26m
- When
- Every day
- Estimated price
- $190–850
Flights from Detroit to Oakland International Airport via Las Vegas
- Ave. Duration
- 7h
- When
- Friday
- Estimated price
- $200–900
- Website
- united.com
Flights from Detroit to San Francisco International Airport
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $150–700
Flights from Detroit to San Francisco International Airport via Denver
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $150–700
Flights from Detroit to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 8h 6m
- When
- Every day
- Estimated price
- $220–950
Flights from Cleveland-Hopkins International Airport to San Francisco International Airport
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $140–650
Flights from Cleveland-Hopkins International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $150–650
Flights from Cleveland-Hopkins International Airport to San Francisco International Airport via Chicago O'Hare
- Ave. Duration
- 7h 43m
- When
- Every day
- Estimated price
- $140–650
- Website
- flyfrontier.com
Flights from Detroit to San Francisco International Airport via Denver
- Ave. Duration
- 7h 17m
- When
- Every day
- Estimated price
- $160–460
Flights from Detroit to Norman Y. Mineta San José International Airport via Las Vegas
- Ave. Duration
- 9h 31m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $270–700
Flights from Detroit to Oakland International Airport via Las Vegas
- Ave. Duration
- 12h 45m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $210–600
- Website
- aa.com
Flights from Detroit to Norman Y. Mineta San José International Airport via Phoenix
- Ave. Duration
- 7h 43m
- When
- Every day
- Estimated price
- $240–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Detroit to Chicago Union Station
- Ave. Duration
- 5h 6m
- Frequency
- 3 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Chicago Union Station to Richmond
- Ave. Duration
- 2d 4h
- Frequency
- Once daily
- Estimated price
- $1,300–2,100
- Website
- Amtrak
Train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtrak
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- $20–35
- Website
- Amtrak
- Phone
- +1-510-464-6000
- Website
- BART
Subway from Richmond to Millbrae
- Ave. Duration
- 1h 17m
- Frequency
- Every 30 minutes
- Estimated price
- $12–16
- Website
- BART
- Adult Single Ride
- $12–16
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Detroit to Indianapolis
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $27–70
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $40–65
- Website
- Greyhound
Bus from St Louis Bus Station to Los Angeles Union Station
- Ave. Duration
- 40h 30m
- Frequency
- Once daily
- Estimated price
- $340–550
- Website
- Greyhound
Bus from Detroit Bus Station to Cleveland Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $28–45
- Website
- Greyhound
- Phone
- +1 714-839-3500
- [email protected]
- Website
- Hoang Bus
Bus from Los Angeles, CA - Chinatown Station to San Jose, CA - Huong Lan Sandwich
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- $45–60
- Book at
- GoToBus - Hoang Express
- Website
- Hoang Bus
- Adult One-way
- $45–60
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Detroit to Palo Alto bus services, operated by Barons Bus, arrive at Indianapolis station.
Palo Alto is 3h behind Detroit. It is currently 5:20 PM in Detroit and 2:20 PM in Palo Alto.
Detroit to Palo Alto train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Detroit to Palo Alto is 2430 miles. It takes approximately 37h 49m to drive from Detroit to Palo Alto.
There are 484+ hotels available in Palo Alto.




















