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How to get fromDetroit to Panama Cityby plane, bus, or car

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There are 8 ways to get from Detroit to Panama City by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Detroit to Northwest Florida Beaches International Airport

    best
    1. Fly from Detroit (DTW) to Northwest Florida Beaches International Airport (ECP)plane plane DTW - ECP
    6h 25m
    $167–632

  2. Fly Detroit to Pensacola International Airport, drive

    cheapest
    1. Fly from Detroit (DTW) to Pensacola International Airport (PNS)plane plane DTW - PNS
    2. Drive from Pensacola-Airport-PNS to Panama Citycar car
    8h 27m
    $111–481

  3. Bus, drive

    1. Take the bus from Detroit Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Orangebus bus
    3. Take the bus from Orange to Crestviewbus bus
    4. Drive from Crestview to Front Beach Rd. & Back Beach Rd.car car
    46h 37m
    $318–552

  4. Drive 980.1 mi

    1. Drive from Detroit to Panama Citycar car 980.1 mi
    17h 4m
    $179–259

  5. Fly Detroit to Destin–Fort Walton Beach Airport, drive

    1. Fly from Detroit (DTW) to Destin–Fort Walton Beach Airport (VPS)plane plane DTW - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    7h 41m
    $114–570

  6. Fly Detroit to Dothan Regional Airport, drive

    1. Fly from Detroit (DTW) to Dothan Regional Airport (DHN)plane plane DTW - DHN
    2. Drive from Dothan Regional Airport (DHN) to Panama Citycar car
    8h 11m
    $113–576

  7. Fly Detroit to Tallahassee, drive

    1. Fly from Detroit (DTW) to Tallahassee (TLH)plane plane DTW - TLH
    2. Drive from Tallahassee (TLH) to Panama Citycar car
    7h 52m
    $149–728

  8. Bus to Cleveland-Hopkins International Airport, fly to Northwest Florida Beaches International Airport

    1. Take the bus from Detroit Bus Station to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Northwest Florida Beaches International Airport (ECP)plane plane CLE - ECP
    8h 48m
    $192–678

Detroit (DTW) to Northwest Florida Beaches International Airport (ECP) flights

Calendar79Weekly Planes
Duration5h 18mAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

Map of how to get from Detroit to Panama City.ExpandLaunch map view
  • Distance: 874.8 mi
  • Duration: 6h 25m

What companies run services between Detroit, MI, USA and Panama City, FL, USA?

Southwest Airlines, Delta, and American Airlines fly from Detroit (DTW) to Northwest Florida Beaches International Airport (ECP) every 2 hours.

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