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How to get fromDetroit to Port Saint Lucieby plane, bus, bus (Greyhound, Flixbus), train, or car

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There are 8 ways to get from Detroit to Port Saint Lucie by plane, bus, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Fort Lauderdale–Hollywood International Airport, bus

    best
    1. Fly from Detroit (DTW) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane DTW - FLL
    2. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    8h 33m
    $192–1,047

  2. Fly to President Donald J. Trump International Airport, bus

    cheapest
    1. Fly from Detroit (DTW) to President Donald J. Trump International Airport (PBI)plane plane DTW - PBI
    2. Take the bus from WPB ITC at BAY D to GATLIN BLVD at I-95 P/R LOTbus bus
    9h 16m
    $151–669

  3. Bus

    1. Take the bus from Detroit Bus Station to Atlanta Bus Stationbus bus Greyhound US0110 / ...
    2. Take the bus from Atlanta Bus Station to Port St Luciebus bus FlixBus N2401
    29h 39m
    $201–369

  4. Bus, train

    1. Take the bus from Detroit Bus Station to Toledo Bus Stopbus bus
    2. Take the train from Toledo to Kissimmee Amtrak Stationtrain train
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    40h 29m
    $518–1,079

  5. Drive 1,220.9 mi

    1. Drive from Detroit to Port Saint Luciecar car 1,220.9 mi
    21h 6m
    $223–322

  6. Fly to Orlando, bus

    1. Fly from Detroit (DTW) to Orlando (MCO)plane plane DTW - MCO
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    8h 59m
    $226–746

  7. Fly to Miami International Airport, bus

    1. Fly from Detroit (DTW) to Miami International Airport (MIA)plane plane DTW - MIA
    2. Take the bus from Sheridan Tri-Rail Station to Fort Piercebus bus
    8h 58m
    $195–648

  8. Fly to Tampa, train, bus

    1. Fly from Detroit (DTW) to Tampa (TPA)plane plane DTW - TPA
    2. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    11h 46m
    $213–800

Detroit to Port Saint Lucie by bus

Calendar7Weekly Buses
Duration29h 39mAverage Duration
Ticket$201Cheapest Price
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Questions & Answers

Map of how to get from Detroit to Port Saint Lucie.ExpandLaunch map view
  • Distance: 1,248.9 mi
  • Duration: 8h 33m

What companies run services between Detroit, MI, USA and Port Saint Lucie, FL, USA?

You can take a bus from Detroit Bus Station to SW PSL Blvd & SE Bayshore Blvd via Atlanta Bus Station and SW Gatlin Blvd & SW Brescia St in around 29h 39m.

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