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How to get fromDetroit to Saint Charlesby train (Amtrak), bus, train, car, plane, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Detroit to Saint Charles by train (Amtrak), bus, train, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Detroit to Chicago Union Stationtrain train Wolverine
    2. Take the train from Chicago OTC to Genevatrain train Up-W
    7h 3m
    $108–209

  2. Drive 315.7 mi

    cheapest
    1. Drive from Detroit to Saint Charlescar car 315.7 mi
    5h 32m
    $58–84

  3. Bus, train

    1. Take the bus from Detroit to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    2. Take the train from Chicago OTC to Genevatrain train Up-W
    8h 46m
    $116–166

  4. Fly Detroit to Chicago O'Hare International Airport, bus

    1. Fly from Detroit (DTW) to Chicago O'Hare International Airport (ORD)plane plane DTW - ORD
    2. Take the bus from Rosemont CTA Station to Elgin Transportation Center Bay 4bus bus
    5h 8m
    $166–706

  5. Bus

    1. Take the bus from Detroit Bus Station to Chicago Bus Stationbus bus Greyhound US0160
    2. Take the bus from Rosemont CTA Station to Elgin Transportation Center Bay 4bus bus 603
    9h 19m
    $79–139

  6. Drive to Capital Region International Airport, fly to Chicago O'Hare International Airport, bus

    1. Drive from Detroit to Lansing-Airport-LANcar car
    2. Fly from Capital Region International Airport (LAN) to Chicago O'Hare International Airport (ORD)plane plane LAN - ORD
    3. Take the bus from Rosemont CTA Station to Elgin Transportation Center Bay 4bus bus
    4h 42m
    $91–378

  7. Fly Detroit to Chicago Midway International Airport, train

    1. Fly from Detroit (DTW) to Chicago Midway International Airport (MDW)plane plane DTW - MDW
    2. Take the train from Chicago OTC to Genevatrain train
    5h 49m
    $151–489

  8. Bus to Bishop International Airport, fly to Chicago O'Hare International Airport, bus

    1. Take the bus from Detroit Bus Station to Flintbus bus
    2. Fly from Bishop International Airport (FNT) to Chicago O'Hare International Airport (ORD)plane plane FNT - ORD
    3. Take the bus from Rosemont CTA Station to Elgin Transportation Center Bay 4bus bus
    5h 51m
    $79–310

  9. Fly Detroit to South Bend, train

    1. Fly from Detroit (DTW) to South Bend (SBN)plane plane DTW - SBN
    2. Take the train from South Bend Airport to Millennium Stationtrain train
    3. Take the train from Chicago OTC to Genevatrain train
    8h 1m
    $105–542

Detroit (DTW) to Chicago O'Hare International Airport (ORD) flights

Calendar130Weekly Planes
Duration1h 34mAverage Duration
Ticket$44Cheapest Price
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Questions & Answers

Map of how to get from Detroit to Saint Charles.ExpandLaunch map view
  • Distance: 319.5 mi
  • Duration: 7h 3m

What companies run services between Detroit, MI, USA and Saint Charles, IL, USA?

You can take a train from Detroit to Saint Charles via Chicago Union Station, Washington & Jefferson, Washington & Canal, Chicago OTC, and Geneva in around 7h 3m. Alternatively, you can take a bus from Detroit Bus Station to Saint Charles via Chicago Bus Station, Chicago, Cumberland, Rosemont, Rosemont CTA Station, and Elgin Transportation Center Bay 4 in around 9h 19m.

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