There are 7 ways to get from Detroit to Saint Marys by bus (Greyhound), bus, train, car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Detroit Bus Station to Pittsburgh Intermodal Stationbus Greyhound US0420
- Take the bus from Pittsburgh, Pa to St Marysbus 510
10h 30m$72–178Drive 350.4 mi
cheapest- Drive from Detroit to Saint Maryscar 350.4 mi
6h 12m$64–93Bus, train
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the train from Toledo to Pittsburgh Amtrak Stationtrain
- Take the bus from Pittsburgh, Pa to St Marysbus 510
12h 16m$109–292Fly to Buffalo Niagara International Airport, bus
- Fly from Detroit (DTW) to Buffalo Niagara International Airport (BUF)plane DTW - BUF
- Take the bus from Buffalo, Ny to St Marysbus
8h 40m$112–726Fly to Pittsburgh International Airport, bus
- Fly from Detroit (DTW) to Pittsburgh International Airport (PIT)plane DTW - PIT
- Take the bus from Pittsburgh, Pa to St Marysbus
9h 38m$580–997Fly to Du Bois-Jefferson County Airport, taxi
- Fly from Detroit (DTW) to Du Bois-Jefferson County Airport (DUJ)plane DTW - DUJ
- Take the taxi from Du Bois-Jefferson County Airport (DUJ) to Saint Marystaxi
6h 52m$66–393Fly to Rochester, bus
- Fly from Detroit (DTW) to Rochester (ROC)plane DTW - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
- Take the bus from Buffalo, Ny to St Marysbus
10h 29m$159–840
Detroit to Saint Marys by bus
Questions & Answers
The cheapest way to get from Detroit to Saint Marys is to drive which costs $60 - $95 and takes 6h 12m.
The fastest way to get from Detroit to Saint Marys is to drive which takes 6h 12m and costs $60 - $95.
No, there is no direct bus from Detroit station to Saint Marys. However, there are services departing from Detroit Bus Station and arriving at St Marys via Pittsburgh, Pa. The journey, including transfers, takes approximately 10h 30m.
The distance between Detroit and Saint Marys is 454 miles. The road distance is 352.5 miles.
The best way to get from Detroit to Saint Marys without a car is to bus which takes 10h 30m and costs $70 - $180.
It takes approximately 10h 30m to get from Detroit to Saint Marys, including transfers.
Detroit to Saint Marys bus services, operated by Greyhound USA, depart from Detroit Bus Station.
Detroit to Saint Marys bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Yes, the driving distance between Detroit to Saint Marys is 352 miles. It takes approximately 6h 12m to drive from Detroit to Saint Marys.
There are 13+ hotels available in Saint Marys.
What companies run services between Detroit, MI, USA and Saint Marys, PA, USA?
You can take a bus from Detroit Bus Station to St Marys via Pittsburgh, Pa in around 10h 30m.
- Website
- delta.com
Flights from Detroit to Buffalo Niagara International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $80–600
Flights from Detroit to Pittsburgh International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $60–420
Flights from Detroit to Rochester
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $100–700
- Website
- iflysouthern.com
Flights from Detroit to Du Bois-Jefferson County Airport via Washington Dulles
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $80–450
Flights from Detroit to Du Bois-Jefferson County Airport via Pittsburgh International Airport
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $55–380
Flights from Detroit to Du Bois-Jefferson County Airport via Chicago Midway, Pittsburgh International Airport
- Ave. Duration
- 7h 30m
- When
- Sunday
- Estimated price
- $90–490
Flights from Detroit to Du Bois-Jefferson County Airport via Toronto, Pittsburgh International Airport
- Ave. Duration
- 7h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–440
Flights from Detroit to Du Bois-Jefferson County Airport via Baltimore, Pittsburgh International Airport
- Ave. Duration
- 8h
- When
- Tuesday and Wednesday
- Estimated price
- $90–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Pittsburgh Amtrak Station
- Ave. Duration
- 5h 16m
- Frequency
- Once daily
- Estimated price
- $75–160
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Detroit Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 5h 35m
- Frequency
- Twice daily
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $11–21
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Pittsburgh, Pa to St Marys
- Saver
- $28–90
- Flexible
- $55–95
Bus from Pittsburgh, Pa to St Marys
- Saver
- $28–90
- Flexible
- $55–95
Bus from Buffalo, Ny to St Marys
- Saver
- $28–90
- Flexible
- $55–95
Bus from Pittsburgh, Pa to St Marys
- Saver
- $28–90
- Flexible
- $55–95
Bus from Buffalo, Ny to St Marys
- Saver
- $28–90
- Flexible
- $55–95
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $5–40
- Website
- Barons Bus
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–19
- Schedules at
- Flixbus USA
- Ave. Duration
- 1h 3m
- Estimated price
- $9–11
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide












