There are 7 ways to get from Detroit to Sanibel by plane, bus (Greyhound, Flixbus), bus, train, taxi, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Detroit to Ft. Myers
best- Fly from Detroit (DTW) to Ft. Myers (RSW)plane DTW - RSW
5h 19m$272–787Bus to Bishop International Airport, fly to Ft. Myers
cheapest- Take the bus from Detroit Bus Station to Flintbus
- Fly from Bishop International Airport (FNT) to Ft. Myers (RSW)plane FNT - RSW
6h 33m$199–699Bus
- Take the bus from Detroit Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus
32h 31m$258–394Bus, train, taxi
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the train from Toledo to Tampatrain
- Take the bus from Tampa to Fort Myers Amtrak Bus Stopbus
- Take the taxi from Fort Myers Amtrak Bus Stop to Sanibeltaxi
43h 55m$506–1,172Drive 1,269 mi
- Drive from Detroit to Sanibelcar 1,269 mi
22h 26m$232–335Bus to Cleveland-Hopkins International Airport, fly to Ft. Myers
- Take the bus from Detroit Bus Station to Cleveland Bus Stationbus
- Fly from Cleveland-Hopkins International Airport (CLE) to Ft. Myers (RSW)plane CLE - RSW
7h 53m$279–778Bus to Bishop International Airport, fly to Punta Gorda Airport, taxi
- Take the bus from Detroit Bus Station to Flintbus
- Fly from Bishop International Airport (FNT) to Punta Gorda Airport (PGD)plane FNT - PGD
- Take the taxi from Punta Gorda Airport (PGD) to Sanibeltaxi
6h 29m$214–634
Detroit (DTW) to Ft. Myers (RSW) flights
Comparing Your Travel Options
The cheapest way to get from Detroit to Sanibel is to drive which costs $230 - $340 and takes 22h 26m.
The fastest way to get from Detroit to Sanibel is to fly which takes 5h 19m and costs $270 - $800.
No, there is no direct bus from Detroit station to Sanibel. However, there are services departing from Detroit Bus Station and arriving at Cape Coral Transfer Center via Atlanta Bus Station, Tampa Bus Station and Rosa Parks Transportation Ctr. The journey, including transfers, takes approximately 32h 31m.
The distance between Detroit and Sanibel is 1140 miles. The road distance is 1276.4 miles.
The best way to get from Detroit to Sanibel without a car is to bus which takes 32h 31m and costs $250 - $400.
It takes approximately 5h 19m to get from Detroit to Sanibel, including transfers.
Detroit to Sanibel bus services, operated by Greyhound USA, depart from Detroit Bus Station.
The best way to get from Detroit to Sanibel is to fly which takes 5h 19m and costs $270 - $800. Alternatively, you can bus, which costs $250 - $400 and takes 32h 31m.
Detroit to Sanibel bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Detroit to Sanibel is 1276 miles. It takes approximately 22h 26m to drive from Detroit to Sanibel.
What companies run services between Detroit, MI, USA and Sanibel, FL, USA?
Frontier Airlines, Delta, and Southwest Airlines fly from Detroit (DTW) to Ft. Myers (RSW) every 2 hours. Alternatively, you can take a bus from Detroit Bus Station to Sanibel via Atlanta Bus Station, Tampa Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 32h 31m.
- Website
- delta.com
Flights from Detroit to Ft. Myers
- Ave. Duration
- 2h 48m
- When
- Every day
- Estimated price
- $150–800
Flights from Detroit to Ft. Myers via Atlanta
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $150–800
Flights from Cleveland-Hopkins International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $140–700
Flights from Cleveland-Hopkins International Airport to Ft. Myers via Detroit
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $150–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Tampa
- Ave. Duration
- 36h 38m
- Frequency
- Once daily
- Estimated price
- $400–1,000
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Detroit Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 20m
- Frequency
- Twice daily
- Estimated price
- $110–190
- Website
- Greyhound
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Detroit Bus Station to Cleveland Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $25–40
- Website
- Greyhound
- Ave. Duration
- 49 min
- Estimated price
- $70–140
EJ Taxi
CT TAXI Transportation LLC
- Phone
- +1 239-218-9590
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 3737+ hotels available in Sanibel.





