There are 7 ways to get from Detroit to Santa Ana by plane, train (Amtrak), bus (Greyhound), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to John Wayne Airport Orange County
best- Fly from Detroit (DTW) to John Wayne Airport Orange County (SNA)plane DTW - SNA
6h 58m$331–4,137Fly to Long Beach Airport
cheapest- Fly from Detroit (DTW) to Long Beach Airport (LGB)plane DTW - LGB
11h 21m$177–759Train (Amtrak)
- Take the train from Detroit to Chicago Union Stationtrain Wolverine
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain Southwest Chief
2d 1h$1,361–2,147Bus
- Take the bus from Detroit to Indianapolisbus
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to El Monte Bus Stopbus
- Take the bus from El Monte to Santa Anabus
2d 5h$422–665Drive 2,275.7 mi
- Drive from Detroit to Santa Anacar 2,275.7 mi
35h 54m$416–600Fly to Los Angeles International Airport, train
- Fly from Detroit (DTW) to Los Angeles International Airport (LAX)plane DTW - LAX
- Take the train from Los Angeles to Santa Anatrain
9h 28m$208–595Fly to San Diego International Airport, train
- Fly from Detroit (DTW) to San Diego International Airport (SAN)plane DTW - SAN
- Take the train from San Diego to Santa Anatrain
10h 12m$254–837
Detroit to Santa Ana by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Detroit to Santa Ana is to fly and train which costs $200 - $600 and takes 9h 28m.
The fastest way to get from Detroit to Santa Ana is to fly which takes 6h 58m and costs $330 - $4,200.
No, there is no direct bus from Detroit to Santa Ana. However, there are services departing from Detroit and arriving at Santa Ana via Indianapolis Union Station, St Louis Bus Station, El Monte Station Upper Level and El Monte. The journey, including transfers, takes approximately 2 days 5h.
No, there is no direct train from Detroit to Santa Ana. However, there are services departing from Detroit and arriving at Santa Ana via Chicago Union Station and Fullerton Amtrak Station. The journey, including transfers, takes approximately 2 days 1h.
The distance between Detroit and Santa Ana is 1994 miles. The road distance is 2289 miles.
The best way to get from Detroit to Santa Ana without a car is to train which takes 2 days 1h and costs $1,300 - $2,200.
It takes approximately 6h 58m to get from Detroit to Santa Ana, including transfers.
Detroit to Santa Ana bus services, operated by Barons Bus, depart from Detroit station.
Detroit to Santa Ana train services, operated by Amtrak, depart from Detroit station.
The best way to get from Detroit to Santa Ana is to fly which takes 6h 58m and costs $330 - $4,200. Alternatively, you can train, which costs $1,300 - $2,200 and takes 2 days 1h, you could also bus, which costs $420 - $700 and takes 2 days 5h.
What companies run services between Detroit, MI, USA and Santa Ana, CA, USA?
Delta, Southwest Airlines, and three other airlines fly from Detroit (DTW) to John Wayne Airport Orange County (SNA) every 3 hours. Alternatively, you can take a train from Detroit to Santa Ana via Chicago Union Station and Fullerton Amtrak Station in around 2d 1h.
- Website
- southwest.com
Flights from Detroit to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 6h 20m
- When
- Sunday
- Estimated price
- $250–1,100
Flights from Detroit to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 41m
- When
- Saturday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $250–1,100
Flights from Detroit to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 7h
- When
- Saturday
- Estimated price
- $250–1,100
Flights from Detroit to Los Angeles International Airport via St. Louis
- Ave. Duration
- 6h 35m
- When
- Sunday
- Estimated price
- $150–650
Flights from Detroit to Los Angeles International Airport via Chicago Midway
- Ave. Duration
- 6h 46m
- When
- Monday to Wednesday
- Estimated price
- $150–650
Flights from Detroit to Los Angeles International Airport via Denver
- Ave. Duration
- 6h 40m
- When
- Saturday
- Estimated price
- $150–650
Flights from Detroit to Los Angeles International Airport via Las Vegas
- Ave. Duration
- 6h 45m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $150–650
Flights from Detroit to San Diego International Airport via Denver
- Ave. Duration
- 6h 41m
- When
- Every day
- Estimated price
- $190–850
Flights from Detroit to San Diego International Airport via St. Louis
- Ave. Duration
- 6h 27m
- When
- Tuesday, Wednesday, Sunday, and Saturday
- Estimated price
- $190–850
Flights from Detroit to San Diego International Airport via Las Vegas
- Ave. Duration
- 6h 55m
- When
- Tuesday to Friday
- Estimated price
- $190–850
Flights from Detroit to San Diego International Airport via Phoenix
- Ave. Duration
- 7h 10m
- When
- Saturday
- Estimated price
- $190–850
Flights from Detroit to Long Beach Airport via Denver
- Ave. Duration
- 7h 42m
- When
- Saturday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $170–750
Flights from Detroit to Long Beach Airport via Phoenix
- Ave. Duration
- 7h 10m
- When
- Saturday
- Estimated price
- $170–750
Flights from Detroit to Long Beach Airport via Las Vegas
- Ave. Duration
- 7h 52m
- When
- Every day
- Estimated price
- $170–750
Flights from Detroit to Long Beach Airport via Chicago Midway
- Ave. Duration
- 7h 50m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $170–750
Flights from Detroit to Long Beach Airport via Nashville
- Ave. Duration
- 10h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $190–800
- Website
- delta.com
Flights from Detroit to John Wayne Airport Orange County
- Ave. Duration
- 4h 53m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,100
Flights from Detroit to John Wayne Airport Orange County via Minneapolis
- Ave. Duration
- 7h 10m
- When
- Every day
- Estimated price
- $260–1,100
Flights from Detroit to John Wayne Airport Orange County via Salt Lake City
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $260–1,100
Flights from Detroit to Los Angeles International Airport
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $150–650
Flights from Detroit to San Diego International Airport
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $190–850
Flights from Detroit to Long Beach Airport via Salt Lake City
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $170–750
- Website
- united.com
Flights from Detroit to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 59m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Detroit to Los Angeles International Airport via Denver
- Ave. Duration
- 6h 43m
- When
- Monday to Saturday
- Estimated price
- $150–650
Flights from Detroit to San Diego International Airport via Denver
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $190–850
- Website
- flyfrontier.com
Flights from Detroit to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 44m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $260–750
Flights from Detroit to Los Angeles International Airport
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $170–410
Flights from Detroit to Los Angeles International Airport via Denver
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $170–410
- Website
- aa.com
Flights from Detroit to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 7h 21m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Detroit to San Diego International Airport via Phoenix
- Ave. Duration
- 6h 52m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Detroit to Chicago Union Station
- Ave. Duration
- 5h 6m
- Frequency
- 3 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $1,200–1,900
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $50–80
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Detroit to Indianapolis
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $27–70
- Website
- Barons Bus
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $40–65
- Website
- Greyhound
Bus from St Louis Bus Station to El Monte Bus Stop
- Ave. Duration
- 40h 10m
- Frequency
- Once daily
- Estimated price
- $330–490
- Website
- Greyhound
- Phone
- +1 866 691 9732
- [email protected]
- Website
- Limousine Express
Bus from El Monte to Santa Ana
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $24–35
- Website
- Limousine Express
- One Way
- $24–35
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
Detroit to Santa Ana bus services, operated by Barons Bus, arrive at Indianapolis station.
Santa Ana is 3h behind Detroit. It is currently 11:29 PM in Detroit and 8:29 PM in Santa Ana.
Detroit to Santa Ana train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Detroit to Santa Ana is 2289 miles. It takes approximately 35h 54m to drive from Detroit to Santa Ana.
Book your Detroit to Santa Ana train tickets online with Omio.
Book your Detroit to Santa Ana bus tickets online with Omio.
There are 1604+ hotels available in Santa Ana.













