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How to get fromDetroit to Santa Anaby plane, train (Amtrak), bus (Greyhound, Amtrak), car, or train

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There are 7 ways to get from Detroit to Santa Ana by plane, train (Amtrak), bus (Greyhound, Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Detroit (DTW) to John Wayne Airport Orange County (SNA)plane plane DTW - SNA
    6h 48m
    $331–4,537

  2. Fly to Los Angeles International Airport, train

    cheapest
    1. Fly from Detroit (DTW) to Los Angeles International Airport (LAX)plane plane DTW - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    9h 22m
    $190–588

  3. Train (Amtrak)

    1. Take the train from Detroit to Chicago Union Stationtrain train Wolverine
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2d 1h
    $798–1,694

  4. Bus

    1. Take the bus from Detroit, MI to Indianapolis, INbus bus
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to Santa Anabus bus
    2d 5h
    $374–763

  5. Drive 2,275.7 mi

    1. Drive from Detroit to Santa Anacar car 2,275.7 mi
    35h 53m
    $416–600

  6. Fly to San Diego International Airport, train

    1. Fly from Detroit (DTW) to San Diego International Airport (SAN)plane plane DTW - SAN
    2. Take the train from San Diego to Santa Anatrain train
    10h 6m
    $234–432

  7. Fly to Long Beach Airport

    1. Fly from Detroit (DTW) to Long Beach Airport (LGB)plane plane DTW - LGB
    11h 20m
    $207–810

Detroit to Santa Ana by train (Amtrak)

Calendar7Weekly Trains
Duration2d 1hAverage Duration
Ticket$798Cheapest Price
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Questions & Answers

Map of how to get from Detroit to Santa Ana.ExpandLaunch map view
  • Distance: 1,982.6 mi
  • Duration: 6h 48m

What companies run services between Detroit, MI, USA and Santa Ana, CA, USA?

Delta, Southwest Airlines, and three other airlines fly from Detroit (DTW) to John Wayne Airport Orange County (SNA) every 3 hours. Alternatively, you can take a train from Detroit to Santa Ana via Chicago Union Station and Fullerton Amtrak Station in around 2d 1h.

Airlines
Train operators
Bus operators

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