There are 7 ways to get from Detroit to Santa Ana by plane, train (Amtrak), bus (Greyhound), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to John Wayne Airport Orange County
best- Fly from Detroit (DTW) to John Wayne Airport Orange County (SNA)plane DTW - SNA
6h 51m$331–4,137Fly to Long Beach Airport
cheapest- Fly from Detroit (DTW) to Long Beach Airport (LGB)plane DTW - LGB
11h 20m$167–709Train (Amtrak)
- Take the train from Detroit to Chicago Union Stationtrain Wolverine
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain Southwest Chief
2d 1h$630–1,471Bus
- Take the bus from Detroit, MI to Indianapolis, INbus
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to El Monte Bus Stopbus
- Take the bus from El Monte to Santa Anabus
2d 5h$377–640Drive 2,275.7 mi
- Drive from Detroit to Santa Anacar 2,275.7 mi
35h 53m$416–600Fly to Los Angeles International Airport, train
- Fly from Detroit (DTW) to Los Angeles International Airport (LAX)plane DTW - LAX
- Take the train from Los Angeles to Santa Anatrain
9h 21m$188–586Fly to San Diego International Airport, train
- Fly from Detroit (DTW) to San Diego International Airport (SAN)plane DTW - SAN
- Take the train from San Diego to Santa Anatrain
10h 7m$228–812
Detroit to Santa Ana by train (Amtrak)
Questions & Answers
The cheapest way to get from Detroit to Santa Ana is to fly and train which costs $180 - $600 and takes 9h 21m.
The fastest way to get from Detroit to Santa Ana is to fly which takes 6h 51m and costs $330 - $4,200.
No, there is no direct bus from Detroit to Santa Ana. However, there are services departing from Detroit, MI and arriving at Santa Ana via Indianapolis Union Station, St Louis Bus Station, El Monte Station Upper Level and El Monte. The journey, including transfers, takes approximately 2 days 5h.
No, there is no direct train from Detroit to Santa Ana. However, there are services departing from Detroit and arriving at Santa Ana via Chicago Union Station and Fullerton Amtrak Station. The journey, including transfers, takes approximately 2 days 1h.
The distance between Detroit and Santa Ana is 1994 miles. The road distance is 2289 miles.
The best way to get from Detroit to Santa Ana without a car is to train which takes 2 days 1h and costs $600 - $1,500.
It takes approximately 6h 51m to get from Detroit to Santa Ana, including transfers.
Detroit to Santa Ana bus services, operated by Barons Bus, depart from Detroit, MI station.
Detroit to Santa Ana train services, operated by Amtrak, depart from Detroit station.
The best way to get from Detroit to Santa Ana is to fly which takes 6h 51m and costs $330 - $4,200. Alternatively, you can train, which costs $600 - $1,500 and takes 2 days 1h, you could also bus, which costs $370 - $650 and takes 2 days 5h.
What companies run services between Detroit, MI, USA and Santa Ana, CA, USA?
Delta, Southwest Airlines, and two other airlines fly from Detroit (DTW) to John Wayne Airport Orange County (SNA) every 3 hours. Alternatively, you can take a train from Detroit to Santa Ana via Chicago Union Station and Fullerton Amtrak Station in around 2d 1h.
- Website
- southwest.com
Flights from Detroit to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 48m
- When
- Monday to Saturday
- Estimated price
- $240–1,100
Flights from Detroit to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 7h 22m
- When
- Monday to Wednesday
- Estimated price
- $240–1,100
Flights from Detroit to Los Angeles International Airport via Las Vegas
- Ave. Duration
- 6h 30m
- When
- Sunday
- Estimated price
- $150–650
Flights from Detroit to Los Angeles International Airport via Denver
- Ave. Duration
- 6h 46m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $150–650
Flights from Detroit to San Diego International Airport via Las Vegas
- Ave. Duration
- 6h 35m
- When
- Monday to Wednesday
- Estimated price
- $200–850
Flights from Detroit to San Diego International Airport via Denver
- Ave. Duration
- 6h 33m
- When
- Monday to Saturday
- Estimated price
- $190–850
Flights from Detroit to San Diego International Airport via St. Louis
- Ave. Duration
- 6h 37m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $190–850
Flights from Detroit to Long Beach Airport via Las Vegas
- Ave. Duration
- 6h 43m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $160–700
Flights from Detroit to Long Beach Airport via Denver
- Ave. Duration
- 6h 30m
- When
- Monday to Wednesday
- Estimated price
- $160–700
Flights from Detroit to Long Beach Airport via Chicago Midway
- Ave. Duration
- 7h 55m
- When
- Tuesday to Friday
- Estimated price
- $160–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Detroit to Chicago Union Station
- Ave. Duration
- 5h 6m
- Frequency
- 3 times a day
- Estimated price
- $70–170
- Website
- Amtrak
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $550–1,300
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $9–21
- Website
- Amtrak
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $24–55
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Detroit, MI to Indianapolis, IN
- Ave. Duration
- 5h 20m
- Frequency
- Twice daily
- Estimated price
- $27–70
- Website
- Barons Bus
Want to know more about travelling around United States
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More Questions & Answers
Detroit to Santa Ana bus services, operated by Barons Bus, arrive at Indianapolis, IN station.
Santa Ana is 3h behind Detroit. It is currently 3:45 PM in Detroit and 12:45 PM in Santa Ana.
Detroit to Santa Ana train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Detroit to Santa Ana is 2289 miles. It takes approximately 35h 53m to drive from Detroit to Santa Ana.
Book your Detroit to Santa Ana train tickets online with Omio.
Book your Detroit to Santa Ana bus tickets online with Omio.
There are 1455+ hotels available in Santa Ana.







