Rome2Rio

How to get fromDetroit to Sikestonby plane, car, train, bus, taxi, bus (Greyhound, Flixbus), or bus (Amtrak)

Find Transport to Sikeston

See all options

There are 10 ways to get from Detroit to Sikeston by plane, car, train, bus, taxi, bus (Greyhound, Flixbus), or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barkley Regional Airport, drive

    best
    1. Fly from Detroit (DTW) to Barkley Regional Airport (PAH)plane plane DTW - PAH
    2. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    7h 7m
    $97–497

  2. Train, bus

    1. Take the train from Detroit to Chicago Union Stationtrain train Wolverine
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    14h 26m
    $192–316

  3. Train, drive (Amtrak)

    1. Take the train from Detroit to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train
    3. Drive from Fulton Amtrak Station to Sikestoncar car
    15h 22m
    $187–424

  4. Drive  603.7 mi

    1. Drive from Detroit to Sikestoncar car 603.7 mi
    10h 14m
    $111–160

  5. Fly to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    7h 49m
    $711–1,105

  6. Fly to Williamson County Regional Airport, bus

    1. Fly from Detroit (DTW) to Williamson County Regional Airport (MWA)plane plane DTW - MWA
    2. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    9h 7m
    $142–583

  7. Fly to Nashville, bus, drive

    1. Fly from Detroit (DTW) to Nashville (BNA)plane plane DTW - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Drive from Paducah Bus Station to Sikestoncar car
    8h 52m
    $443–1,151

  8. Fly to Memphis, bus

    1. Fly from Detroit (DTW) to Memphis (MEM)plane plane DTW - MEM
    2. Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus bus
    9h 3m
    $228–1,018

  9. Bus

    1. Take the bus from Detroit Bus Station to Chicago Bus Stationbus bus Greyhound US0160
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    16h 10m
    $152–219

  10. Bus via Woodward & Baltimore

    1. Take the bus from Detroit to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    16h 51m
    $198–274

Detroit (DTW) to Barkley Regional Airport (PAH) flights

Calendar21Weekly Planes
Duration5hAverage Duration
Ticket$86Cheapest Price
See schedules

Questions & Answers

Map of how to get from Detroit to Sikeston.ExpandLaunch map view
  • Distance: 534.1 mi
  • Duration: 7h 7m

What companies run services between Detroit, MI, USA and Sikeston, MO, USA?

You can take a bus from Detroit Bus Station to Sikeston via Chicago Bus Station, Harrison & Jefferson, Cicero & 24th Place Terminal, Tornado Bus Co - Chicago, and Flying J - Matthews in around 16h 10m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers