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How to get fromDetroit to Tupeloby plane, car, bus (Greyhound, Flixbus), train, bus, or bus (Greyhound)

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There are 10 ways to get from Detroit to Tupelo by plane, car, bus (Greyhound, Flixbus), train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Birmingham–Shuttlesworth International Airport, drive

    best
    1. Fly from Detroit (DTW) to Birmingham–Shuttlesworth International Airport (BHM)plane plane DTW - BHM
    2. Drive from Birmingham-Airport-BHM to Tupelocar car
    6h 12m
    $156–792

  2. Fly to Tupelo Regional Airport

    cheapest
    1. Fly from Detroit (DTW) to Tupelo Regional Airport (TUP)plane plane DTW - TUP
    5h 44m
    $96–460

  3. Bus

    1. Take the bus from Detroit Bus Station to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    18h 14m
    $139–262

  4. Train, bus via St. Louis

    1. Take the train from Detroit to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    19h 26m
    $254–501

  5. Drive 723.1 mi

    1. Drive from Detroit to Tupelocar car 723.1 mi
    13h 22m
    $132–191

  6. Fly to Golden Triangle Regional Airport, drive

    1. Fly from Detroit (DTW) to Golden Triangle Regional Airport (GTR)plane plane DTW - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    7h 17m
    $108–509

  7. Fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Fly from Detroit (DTW) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane DTW - HSV
    2. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    6h 16m
    $115–537

  8. Fly to Memphis, bus

    1. Fly from Detroit (DTW) to Memphis (MEM)plane plane DTW - MEM
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    7h 58m
    $159–796

  9. Train, bus

    1. Take the train from Detroit to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    18h 24m
    $199–386

  10. Bus via Atlanta (Greyhound)

    1. Take the bus from Detroit Bus Station to Atlanta Bus Stationbus bus Greyhound US0110 / ...
    2. Take the bus from Atlanta Bus Station to Tupelobus bus Greyhound US0610
    23h 19m
    $165–304

Detroit (DTW) to Birmingham–Shuttlesworth International Airport (BHM) flights

Calendar78Weekly Planes
Duration3h 45mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

Map of how to get from Detroit to Tupelo.ExpandLaunch map view
  • Distance: 781.5 mi
  • Duration: 6h 12m

What companies run services between Detroit, MI, USA and Tupelo, MS, USA?

You can take a bus from Detroit Bus Station to Tupelo via Nashville Bus Station, Memphis Bus Station, and Tupelo in around 18h 14m. Alternatively, Delta and Corporate Flight Management Inc fly from Detroit (DTW) to Tupelo Regional Airport (TUP) twice daily.

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