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How to get fromDevils Lake to Mayo Clinicby train, bus, car, or plane

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There are 7 ways to get from Devils Lake to Mayo Clinic by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Devils Lake Amtrak Station to St. Paul-Minneapolistrain train Empire Builder
    2. Take the bus from St. Paul to Rochesterbus bus Jefferson Lines 965
    10h 22m
    $134–272

  2. Train to Grand Forks International Airport, fly to Rochester

    cheapest
    1. Take the train from Devils Lake Amtrak Station to Grand Forks Stationtrain train
    2. Fly from Grand Forks International Airport (GFK) to Rochester (RST)plane plane GFK - RST
    8h 56m
    $84–432

  3. Drive  480 mi

    1. Drive from Devils Lake to Mayo Cliniccar car 480 mi
    8h 6m
    $88–127

  4. Drive to Minot International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from Devils Lake to Minot International Airport (MOT)car car
    2. Fly from Minot International Airport (MOT) to Minneapolis–Saint Paul International Airport (MSP)plane plane MOT - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 37m
    $144–514

  5. Train to Grand Forks International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Devils Lake Amtrak Station to Grand Forks Stationtrain train
    2. Fly from Grand Forks International Airport (GFK) to Minneapolis–Saint Paul International Airport (MSP)plane plane GFK - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 48m
    $140–504

  6. Drive to Thief River Falls, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from Devils Lake to Thief River Falls (TVF)car car
    2. Fly from Thief River Falls (TVF) to Minneapolis–Saint Paul International Airport (MSP)plane plane TVF - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 38m
    $227–329

  7. Drive to Bismarck Municipal Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from Devils Lake to Bismarck-Airport-BIScar car
    2. Fly from Bismarck Municipal Airport (BIS) to Minneapolis–Saint Paul International Airport (MSP)plane plane BIS - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 36m
    $150–519

Devils Lake to Mayo Clinic by train, bus, and foot

Calendar7Weekly Services
Duration10h 22mAverage Duration
Ticket$134Cheapest Price
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Comparing Your Travel Options

Map of how to get from Devils Lake to Mayo Clinic.ExpandLaunch map view
  • Distance: 486.7 mi
  • Duration: 10h 22m

What companies run services between Devils Lake, ND, USA and Mayo Clinic, MN, USA?

There is no direct connection from Devils Lake to Mayo Clinic. However, you can take the train to St. Paul-Minneapolis, walk to St. Paul, take the bus to Rochester, then walk to Mayo Clinic. Alternatively, you can drive from Devils Lake to Mayo Clinic in around 8h 6m.

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