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How to get fromDevils Lake to Mayo Clinicby train, bus, car, or plane

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There are 5 ways to get from Devils Lake to Mayo Clinic by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Devils Lake Amtrak Station to St. Paul-Minneapolistrain train Empire Builder
    2. Take the bus from St. Paul to Rochester, MNbus bus Minneapolis / ...
    10h 27m
    $161–307

  2. Drive 480 mi

    cheapest
    1. Drive from Devils Lake to Mayo Cliniccar car 480 mi
    8h 6m
    $88–127

  3. Train, bus via Detroit Lakes

    1. Take the train from Devils Lake Amtrak Station to Detroit Lakes Amtrak Stationtrain train
    2. Take the bus from Detroit Lakes to Brainerdbus bus
    3. Take the bus from Perkins Restaurant & Bakery - Brainerd to Minneapolis / St Paul Airportbus bus
    4. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    14h 23m
    $208–291

  4. Train, fly to Rochester

    1. Take the train from Devils Lake Amtrak Station to Grand Forks Stationtrain train
    2. Fly from Grand Forks International Airport (GFK) to Rochester (RST)plane plane GFK - RST
    7h 10m
    $103–400

  5. Train, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Devils Lake Amtrak Station to Grand Forks Stationtrain train
    2. Fly from Grand Forks International Airport (GFK) to Minneapolis–Saint Paul International Airport (MSP)plane plane GFK - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 49m
    $146–481

Devils Lake to Mayo Clinic by train, bus, and foot

Calendar14Weekly Services
Duration10h 27mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

Map of how to get from Devils Lake to Mayo Clinic.ExpandLaunch map view
  • Distance: 487 mi
  • Duration: 10h 27m

What companies run services between Devils Lake, ND, USA and Mayo Clinic, MN, USA?

There is no direct connection from Devils Lake to Mayo Clinic. However, you can take the train to St. Paul-Minneapolis, walk to St. Paul, take the bus to Rochester, MN, then walk to Mayo Clinic. Alternatively, you can take a train from Devils Lake Amtrak Station to Mayo Clinic via Detroit Lakes Amtrak Station, Detroit Lakes, Brainerd, Perkins Restaurant & Bakery - Brainerd, Minneapolis / St Paul Airport, and Groome Transportation Office - Rochester in around 14h 23m.

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