There are 14 ways to get from Domodossola to Sicily by bus, plane, train, ferry, car, car ferry, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Milano Malpensa Airport, fly to Catania–Fontanarossa Airport
best- Take the bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1bus
- Fly from Milano Malpensa Airport (MXP) to Catania–Fontanarossa Airport (CTA)plane MXP - CTA
4h 27m€30–183Bus to Milano Malpensa Airport, fly to Palermo Airport
cheapest- Take the bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1bus
- Fly from Milano Malpensa Airport (MXP) to Palermo Airport (PMO)plane MXP - PMO
4h 53m€24–234Train, ferry
- Take the train from Domodossola to Milano Centraletrain Ec
- Take the train from Milano Centrale to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
15h 44mDrive, car ferry
- Drive from Domodossola to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
23h 17m€140–208Bus
- Take the bus from Domodossola to Rho Fiera Milanobus Re4
- Take the bus from Milano, Autostazione Lampugnano to Palermobus N597
25h 4mTrain to Milan Linate Airport, fly to Palermo Airport
- Take the train from Domodossola to Milano P.Garibalditrain
- Fly from Milan Linate Airport (LIN) to Palermo Airport (PMO)plane LIN - PMO
6h 1m€64–239Train to Milan Linate Airport, fly to Catania–Fontanarossa Airport
- Take the train from Domodossola to Milano P.Garibalditrain
- Fly from Milan Linate Airport (LIN) to Catania–Fontanarossa Airport (CTA)plane LIN - CTA
5h 45m€65–208Train to Milan Linate Airport, fly to Vincenzo Magliocco Airport
- Take the train from Domodossola to Milano P.Garibalditrain
- Fly from Milan Linate Airport (LIN) to Vincenzo Magliocco Airport (CIY)plane LIN - CIY
5h 43m€122–600Train, bus to Il Caravaggio International Airport, fly to Catania–Fontanarossa Airport
- Take the train from Domodossola to Milano Centraletrain
- Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus
- Fly from Il Caravaggio International Airport (BGY) to Catania–Fontanarossa Airport (CTA)plane BGY - CTA
5h 43m€77–322Train, train to Turin Caselle Airport, fly to Catania–Fontanarossa Airport
- Take the train from Domodossola to Novaratrain
- Take the train from Novara to Torino Porta Susatrain
- Fly from Turin Caselle Airport (TRN) to Catania–Fontanarossa Airport (CTA)plane TRN - CTA
6h 41m€48–227Train, bus to Il Caravaggio International Airport, fly to Trapani Airport
- Take the train from Domodossola to Milano Centraletrain
- Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus
- Fly from Il Caravaggio International Airport (BGY) to Trapani Airport (TPS)plane BGY - TPS
6h 41m€81–511Train
- Take the train from Domodossola to Rho-Fiera Milanotrain Re
- Take the train from Milano Rogoredo to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
18h 33m€169–300Train, bus
- Take the train from Domodossola to Locarno FARTtrain 72 / ...
- Take the bus from Bellinzona to Palermo Piazza Cairolibus
27h 36m€229–326Train, car ferry
- Take the train from Domodossola to Novaratrain Re
- Take the train from Novara to Alessandriatrain Re
- Take the train from Alessandria to Genova P.Za Principetrain Re
- Take the carferry from Port of Genoa to Port of Palermocarferry
28h 12m€127–194
Milano Malpensa Airport (MXP) to Catania–Fontanarossa Airport (CTA) flights
Comparing Your Travel Options
The cheapest way to get from Domodossola to Sicily is to bus and fly which costs €29 - €190 and takes 4h 27m.
The fastest way to get from Domodossola to Sicily is to bus and fly which takes 4h 27m and costs €29 - €190.
No, there is no direct bus from Domodossola to Sicily. However, there are services departing from Domodossola and arriving at Piazza Boiardo via Milano, Autostazione Lampugnano and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 25h 4m.
No, there is no direct train from Domodossola to Sicily. However, there are services departing from Domodossola and arriving at Palermo Notarbartolo via Milano Rogoredo, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 18h 33m.
The distance between Domodossola and Sicily is 1146 km.
The best way to get from Domodossola to Sicily without a car is to train and ferry which takes 15h 44m and costs .
It takes approximately 4h 27m to get from Domodossola to Sicily, including transfers.
Domodossola to Sicily bus services, operated by Trenord, depart from Domodossola station.
Domodossola to Sicily train services, operated by Trenitalia, depart from Domodossola station.
The best way to get from Domodossola to Sicily is to bus which takes 25h 4m and costs . Alternatively, you can train, which costs €160 - €300 and takes 18h 33m.
What companies run services between Domodossola, Italy and Sicily, Italy?
You can take a bus from Domodossola to Piazza Boiardo via Rho Fiera Milano, Rho Fieramilano, Lampugnano, Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 25h 4m. Alternatively, you can take a train from Domodossola to Palermo Notarbartolo via Milano Rogoredo, Roma Termini, and Palermo Centrale in around 18h 33m.
- Website
- ryanair.com
Flights from Milano Malpensa Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €50–170
Flights from Milano Malpensa Airport to Catania–Fontanarossa Airport via Naples
- Ave. Duration
- 4h 15m
- When
- Wednesday and Thursday
- Estimated price
- €50–170
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €40–150
Flights from Il Caravaggio International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €45–220
Flights from Turin Caselle Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- €30–240
Flights from Il Caravaggio International Airport to Trapani Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €40–410
Flights from Il Caravaggio International Airport to Trapani Airport via Bari
- Ave. Duration
- 4h 15m
- When
- Monday
- Estimated price
- €40–410
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Domodossola to Milano Centrale
- Ave. Duration
- 1h 33m
- Frequency
- 4 times a week
- Estimated price
- €30–75
- Website
- Trenitalia Eurocity
- 1st Class
- €50–75
- 2nd Class
- €30–45
Train from Domodossola to Milano Centrale
- Ave. Duration
- 1h 33m
- Frequency
- 4 times a week
- Estimated price
- €30–75
- Website
- Trenitalia Eurocity
- 1st Class
- €50–75
- 2nd Class
- €30–45
Train from Domodossola to Milano Centrale
- Ave. Duration
- 1h 33m
- Frequency
- 4 times a week
- Estimated price
- €30–75
- Website
- Trenitalia Eurocity
- 1st Class
- €50–75
- 2nd Class
- €30–45
- Phone
- +39 0322 844 862
- [email protected]
- Website
- Comazzi Bus
Bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- €9
- Website
- Comazzi Bus
Bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- €9
- Website
- Comazzi Bus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Travelling by boat in Italy
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Domodossola to Sicily bus services, operated by Trenord, arrive at Rho Fiera Milano station.
Domodossola to Sicily train services, operated by Trenitalia, arrive at Rho-Fiera Milano station.
Book your Domodossola to Sicily train tickets online with Omio.
There are 6187+ hotels available in Sicily.









