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How to get fromDomodossola to Sienaby train, bus, car, or plane

Find Transport to Siena

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There are 5 ways to get from Domodossola to Siena by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Domodossola to Milano Centraletrain train Ec
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    5h 42m
    €68–166
  2. Bus

    cheapest
    1. Take the bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1bus bus 3
    2. Take the bus from Milan Malpensa Airport 1 P13 to Siena Central Train Stationbus bus Itabus
    9h 10m
    €33–59
  3. Bus via Florence

    1. Take the bus from Domodossola to Milano Centralebus bus Re4
    2. Take the bus from Milano - Famagosta to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    8h 44m
  4. Drive  489.6 km

    1. Drive from Domodossola to Sienacar car 489.6 km
    4h 57m
    €78–113
  5. Bus, fly, train

    1. Take the bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1bus bus
    2. Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane plane MXP - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 13m
    €122–249

Domodossola to Siena by train and bus

Calendar2Weekly Services
Duration5h 42mAverage Duration
Ticket€68Cheapest Price
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Questions & Answers

What companies run services between Domodossola, Italy and Siena, Italy?

You can take a bus from Domodossola to Siena via Milano Centrale, Milano, Stazione Centrale, famagosta m2, Milano - Famagosta, and Florence Villa Constanza Bus Station in around 8h 44m.

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Bus operators

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