What is the cheapest way to get from Domodossola to Siena?

The cheapest way to get from Domodossola to Siena is to bus which costs €35 - €65 and takes 9h 10m.

What is the fastest way to get from Domodossola to Siena?

The fastest way to get from Domodossola to Siena is to drive which takes 4h 57m and costs €75 - €120.

Is there a direct bus between Domodossola and Siena?

No, there is no direct bus from Domodossola to Siena. However, there are services departing from Domodossola and arriving at Siena via Milano, Stazione Centrale, Milano - Famagosta and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 8h 42m.

Is there a direct train between Domodossola and Siena?

No, there is no direct train from Domodossola to Siena. However, there are services departing from Domodossola and arriving at Siena via Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 5h 41m.

How far is it from Domodossola to Siena?

The distance between Domodossola and Siena is 519 km. The road distance is 489.6 km.

How do I travel from Domodossola to Siena without a car?

The best way to get from Domodossola to Siena without a car is to train which takes 5h 41m and costs €70 - €190.

How long does it take to get from Domodossola to Siena?

It takes approximately 5h 41m to get from Domodossola to Siena, including transfers.

Where do I catch the Domodossola to Siena bus from?

Domodossola to Siena bus services, operated by Trenord, depart from Domodossola station.

Where do I catch the Domodossola to Siena train from?

Domodossola to Siena train services, operated by Trenitalia EuroCity, depart from Domodossola station.

Train or bus from Domodossola to Siena?

The best way to get from Domodossola to Siena is to train which takes 5h 41m and costs €70 - €190. Alternatively, you can bus via Florence, which costs and takes 8h 42m.

Where does the Domodossola to Siena bus arrive?

Domodossola to Siena bus services, operated by Trenord, arrive at Milano Centrale station.

Where does the Domodossola to Siena train arrive?

Domodossola to Siena train services, operated by Trenitalia EuroCity, arrive at Milano Centrale station.

Can I drive from Domodossola to Siena?

Yes, the driving distance between Domodossola to Siena is 490 km. It takes approximately 4h 57m to drive from Domodossola to Siena.

How do I get a train ticket from Domodossola to Siena?

Book your Domodossola to Siena train tickets online with Omio.

Where can I stay near Siena?

There are 2536+ hotels available in Siena.

Domodossola to Siena - 6 ways to travel via train, bus, car, and plane

How to get fromDomodossola to Siena

Travel from

See all options

Search accommodation with Expedia

There are 6 ways to get from Domodossola to Siena by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train
best
1. Take the train from Domodossola to Milano Centraletrain Ec
2. Take the train from Milano Centrale to Firenze S.M.N.train Fr
3. Take the train from Firenze S.M.N. to Sienatrain Re
5h 41m
€74–184
Bus
cheapest
1. Take the bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1bus 3
2. Take the bus from Milan Malpensa Airport 1 P13 to Siena Central Train Stationbus Itabus
9h 10m
€36–64
Bus via Florence
1. Take the bus from Domodossola to Milano Centralebus Re4
2. Take the bus from Milano - Famagosta to Florence Villa Constanza Bus Stationbus
3. Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
8h 42m
Drive 489.6 km
1. Drive from Domodossola to Sienacar 489.6 km
4h 57m
€77–111
Bus, fly, train
1. Take the bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1bus
2. Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane MXP - FLR
3. Take the train from Firenze S.M.N. to Sienatrain
8h 17m
€112–220
Train via Rho (Trenitalia)
1. Take the train from Domodossola to Rho-Fiera Milanotrain Re
2. Take the train from Rho-Fiera Milano to Firenze S.M.N.train Fr
3. Take the train from Firenze S.M.N. to Sienatrain Re
7h 21m
€70–136

Domodossola to Siena by train

18Weekly Trains

5h 41mAverage Duration

€74Cheapest Price

See schedules

Questions & Answers

Map of how to get from Domodossola to Siena.

Launch map view

Distance: 518.5 km
Duration: 5h 41m

What companies run services between Domodossola, Italy and Siena, Italy?

You can take a train from Domodossola to Siena via Milano Centrale and Firenze S.M.N. in around 5h 41m. Alternatively, you can take a bus from Domodossola to Siena via Milano Centrale, Milano, Stazione Centrale, famagosta m2, Milano - Famagosta, and Florence Villa Constanza Bus Station in around 8h 42m.

Airlines

Train operators

Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.