There are 7 ways to get from Dothan to Louisville by plane, bus (Greyhound, Amtrak, Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Dothan Regional Airport to Louisville International Airport
best- Fly from Dothan Regional Airport (DHN) to Louisville International Airport (SDF)plane DHN - SDF
5h 47m$110–663Fly Dothan Regional Airport to Blue Grass Airport, drive
cheapest- Fly from Dothan Regional Airport (DHN) to Blue Grass Airport (LEX)plane DHN - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
5h$77–389Bus via Nashville
- Take the bus from Dothan to Nashville Bus Stationbus Greyhound US0115
- Take the bus from Nashville Bus Station to Louisville Bus Stationbus Greyhound US0105 / ...
12h 20m$89–143Drive 557.1 mi
- Drive from Dothan to Louisvillecar 557.1 mi
9h 25m$102–147Drive to Northwest Florida Beaches International Airport, fly to Louisville International Airport
- Drive from Dothan to Northwest Florida Beaches International Airport (ECP)car
- Fly from Northwest Florida Beaches International Airport (ECP) to Louisville International Airport (SDF)plane ECP - SDF
6h 16m$126–674Drive to Destin–Fort Walton Beach Airport, fly to Louisville International Airport
- Drive from Dothan to Destin–Fort Walton Beach Airport (VPS)car
- Fly from Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF)plane VPS - SDF
5h 19m$119–679Bus (Greyhound)
- Take the bus from Dothan to Montgomery Intermodal Centerbus Greyhound US0115
- Take the bus from Montgomery Intermodal Center to Louisville Bus Stationbus Greyhound US0112
14h 25m$91–156
Dothan to Louisville by bus
Comparing Your Travel Options
The cheapest way to get from Dothan to Louisville is to bus via Nashville which costs $85 - $150 and takes 12h 20m.
The fastest way to get from Dothan to Louisville is to fly and drive which takes 5h and costs $75 - $390.
No, there is no direct bus from Dothan to Louisville station. However, there are services departing from Dothan and arriving at Louisville Bus Station via Nashville Bus Station. The journey, including transfers, takes approximately 12h 20m.
The distance between Dothan and Louisville is 492 miles. The road distance is 560.4 miles.
The best way to get from Dothan to Louisville without a car is to bus via Nashville which takes 12h 20m and costs $85 - $150.
It takes approximately 5h 47m to get from Dothan to Louisville, including transfers.
Dothan to Louisville bus services, operated by Greyhound USA, depart from Dothan station.
The best way to get from Dothan to Louisville is to fly which takes 5h 47m and costs $110 - $700. Alternatively, you can bus via Nashville, which costs $85 - $150 and takes 12h 20m.
Dothan to Louisville bus services, operated by Greyhound USA, arrive at Nashville Bus Station.
Louisville is 1h ahead of Dothan. It is currently 4:35 AM in Dothan and 5:35 AM in Louisville.
What companies run services between Dothan, AL, USA and Louisville, KY, USA?
Delta flies from Dothan Regional Airport (DHN) to Louisville International Airport (SDF) 3 times a day. Alternatively, you can take a bus from Dothan to Louisville Bus Station via Nashville Bus Station in around 12h 20m.
- Website
- delta.com
Flights from Dothan Regional Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $100–650
Flights from Dothan Regional Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $55–360
Flights from Northwest Florida Beaches International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $110–650
Flights from Destin–Fort Walton Beach Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $110–650
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Dothan to Nashville Bus Station
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $60–100
- Website
- Greyhound
Bus from Nashville Bus Station to Louisville Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Every 4 hours
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Dothan to Montgomery Intermodal Center
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $16–26
- Website
- Greyhound
Bus from Montgomery Intermodal Center to Louisville Bus Station
- Ave. Duration
- 11h 15m
- Frequency
- Once daily
- Estimated price
- $75–130
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Yes, the driving distance between Dothan to Louisville is 560 miles. It takes approximately 9h 25m to drive from Dothan to Louisville.
Book your Dothan to Louisville bus tickets online with Omio and FlixBus.
There are 622+ hotels available in Louisville.