Rome2Rio

How to get fromDowningtown to Buffaloby train, plane, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)

Find Transport to Buffalo

See all options

There are 9 ways to get from Downingtown to Buffalo by train, plane, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    5h
    $124–809

  2. Drive  331.4 mi

    cheapest
    1. Drive from Downingtown to Buffalocar car 331.4 mi
    6h 47m
    $61–88

  3. Train, bus

    1. Take the train from Downingtown to Gray 30th St Stationtrain train Pao
    2. Take the bus from Philadelphia 30th St Station to Scrantonbus bus
    3. Take the bus from Scranton Bus Station to Buffalobus bus
    11h 43m
    $98–155

  4. Train (Amtrak)

    1. Take the train from Downingtown Amtrak to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    11h 59m
    $307–473

  5. Train to Philadelphia International Airport, fly to Rochester, bus

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 24m
    $178–1,023

  6. Train, train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    6h 8m
    $141–1,355

  7. Train, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    3. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    6h 32m
    $142–675

  8. Train, train to Ronald Reagan Washington National Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Buffalo Niagara International Airport (BUF)plane plane DCA - BUF
    6h 59m
    $176–1,562

  9. Bus

    1. Take the bus from Philadelphia Bus Station to Newark Penn Stationbus bus Greyhound US0421 / ...
    2. Take the bus from Newark Penn Station to Buffalobus bus FlixBus 2686 / ...
    13h 52m
    $80–145

Downingtown to Buffalo by train and bus

Calendar7Weekly Services
Duration11h 43mAverage Duration
Ticket$98Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Downingtown to Buffalo.ExpandLaunch map view
  • Distance: 327.1 mi
  • Duration: 5h

What companies run services between Downingtown, PA, USA and Buffalo, NY, USA?

You can take a train from Downingtown Amtrak to Buffalo via Ny Moynihan Train Hall At Penn Station in around 11h 59m. Alternatively, you can take a bus from Lancaster Av & Green St - MBNS to Buffalo via West Chester Transit Center, 69th St Transit Center, 69th St Transit Center South Terminal, Chestnut St & 12th St, Philadelphia Bus Station, and Newark Penn Station in around 13h 52m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There