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How to get fromDowningtown to Ithacaby train, bus, car, or plane

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There are 7 ways to get from Downingtown to Ithaca by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Downingtown Amtrak to Newark Penn Stationtrain train Keystone Service
    2. Take the bus from Newark Penn Station to Ithacabus bus FlixBus N2687
    7h 22m
    $58–114

  2. Drive  219.4 mi

    cheapest
    1. Drive from Downingtown to Ithacacar car 219.4 mi
    4h 27m
    $40–58

  3. Train to John F. Kennedy International Airport, fly to Ithaca Tompkins Regional Airport

    1. Take the train from Downingtown Amtrak to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Ithaca Tompkins Regional Airport (ITH)plane plane JFK - ITH
    6h 40m
    $79–378

  4. Bus

    1. Take the bus from Philadelphia 30th St Station to Scrantonbus bus Philadelphia
    2. Take the bus from Scranton, Pa to Ithacabus bus 246
    10h 5m
    $80–153

  5. Train, bus via Scranton

    1. Take the train from Downingtown to Jefferson Stationtrain train Pao
    2. Take the bus from Philadelphia Bus Station to Scranton Bus Stationbus bus
    3. Take the bus from Scranton, Pa to Ithacabus bus 246
    11h 23m
    $47–110

  6. Train to Philadelphia International Airport, fly to Rochester, bus

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    3. Take the bus from Rochester to Ithacabus bus
    6h 48m
    $149–851

  7. Train to Philadelphia International Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Syracuse Hancock International Airport (SYR)plane plane PHL - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    7h 3m
    $132–863

Downingtown to Ithaca by train and bus

Calendar5Weekly Services
Duration7h 22mAverage Duration
Ticket$58Cheapest Price
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Comparing Your Travel Options

Map of how to get from Downingtown to Ithaca.ExpandLaunch map view
  • Distance: 326.6 mi
  • Duration: 7h 22m

What companies run services between Downingtown, PA, USA and Ithaca, NY, USA?

You can take a bus from Lancaster Av & Green St - MBNS to Ithaca via West Chester Transit Center, 69th St Transit Center, 69th St Transit Center South Terminal, Market St & 30th St, Philadelphia 30th St Station, and Scranton, Pa in around 10h 5m.

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