Rome2Rio

How to get fromDowningtown to Louisvilleby train, plane, car, bus, subway, or bus (Greyhound, Amtrak)

Find Transport to Louisville

See all options

There are 10 ways to get from Downingtown to Louisville by train, plane, car, bus, subway, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly to Blue Grass Airport, drive

    best
    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Blue Grass Airport (LEX)plane plane PHL - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 30m
    $216–1,142

  2. Train, bus

    cheapest
    1. Take the train from Downingtown Amtrak to Harrisburgtrain train
    2. Take the bus from Harrisburg Bus Station to Cincinnatibus bus
    3. Take the bus from Cincinnati to Louisvillebus bus
    16h 22m
    $113–234

  3. Train, bus via Indianapolis

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    26h 9m
    $302–665

  4. Drive 634.4 mi

    1. Drive from Downingtown to Louisvillecar car 634.4 mi
    11h 7m
    $116–168

  5. Train to Philadelphia International Airport, fly to Louisville International Airport

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Louisville International Airport (SDF)plane plane PHL - SDF
    5h 47m
    $144–776

  6. Train, train to Baltimore-Washington International Airport, fly to Louisville International Airport

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    6h 29m
    $135–1,273

  7. Train, train to Ronald Reagan Washington National Airport, fly to Louisville International Airport

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    7h 24m
    $185–1,530

  8. Train, subway to Washington Dulles International Airport, fly to Louisville International Airport

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    4. Fly from Washington Dulles International Airport (IAD) to Louisville International Airport (SDF)plane plane IAD - SDF
    7h 54m
    $125–1,149

  9. Train to Philadelphia International Airport, fly to Covington, bus

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Covington (CVG)plane plane PHL - CVG
    3. Take the bus from Cincinnati to Louisvillebus bus
    8h 6m
    $184–870

  10. Bus

    1. Take the bus from Norristown to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus Greyhound US0100 / ...
    21h 49m
    $131–254

Downingtown to Louisville by train, bus, and foot

Calendar4Weekly Services
Duration16h 22mAverage Duration
Ticket$113Cheapest Price
See schedules

Questions & Answers

Map of how to get from Downingtown to Louisville.ExpandLaunch map view
  • Distance: 628.9 mi
  • Duration: 5h 30m

What companies run services between Downingtown, PA, USA and Louisville, KY, USA?

You can take a bus from Lancaster Av & Green St - MBNS to Louisville Bus Station via West Chester Transit Center, Plaza at King of Prussia, South Gulph Rd & DeKalb Pk - FS, Norristown, and Indianapolis Union Station in around 21h 49m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound