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How to get fromDowningtown to Syracuseby train, bus, train (Amtrak), car, plane, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Downingtown to Syracuse by train, bus, train (Amtrak), car, plane, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Downingtown to Gray 30th St Stationtrain train Pao
    2. Take the bus from Philadelphia 30th St Station to Scrantonbus bus
    3. Take the bus from Scranton Bus Station to Syracuse Bus Stationbus bus
    8h 42m
    $73–118

  2. Drive 243.9 mi

    cheapest
    1. Drive from Downingtown to Syracusecar car 243.9 mi
    4h 40m
    $45–65

  3. Train (Amtrak)

    1. Take the train from Downingtown Amtrak to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Syracuse Regional Transportation Centertrain train Empire Service / ...
    9h 3m
    $128–270

  4. Train to Philadelphia International Airport, fly to Syracuse Hancock International Airport

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Syracuse Hancock International Airport (SYR)plane plane PHL - SYR
    5h 22m
    $114–732

  5. Train via Albany

    1. Take the train from Downingtown Amtrak to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Albany-Rensselaer Amtrak Stationtrain train
    3. Take the train from Albany-Rensselaer Amtrak Station to Syracuse Regional Transportation Centertrain train
    9h 36m
    $118–365

  6. Bus

    1. Take the bus from Philadelphia Bus Station to Newark Penn Stationbus bus FlixBus 2601 / ...
    2. Take the bus from Newark Penn Station to Syracuse Bus Stationbus bus FlixBus 2685 / ...
    10h 44m
    $55–102

  7. Train to Philadelphia International Airport, fly to Rochester, train

    1. Take the train from Downingtown Amtrak to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    3. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    6h 13m
    $152–916

  8. Train to Laguardia Airport, fly to Syracuse Hancock International Airport

    1. Take the train from Downingtown Amtrak to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane plane LGA - SYR
    7h 13m
    $132–741

Downingtown to Syracuse by train and bus

Calendar7Weekly Services
Duration8h 42mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

Map of how to get from Downingtown to Syracuse.ExpandLaunch map view
  • Distance: 301.9 mi
  • Duration: 8h 42m

What companies run services between Downingtown, PA, USA and Syracuse, NY, USA?

You can take a train from Downingtown Amtrak to Syracuse Regional Transportation Center via Ny Moynihan Train Hall At Penn Station in around 9h 3m. Alternatively, you can take a bus from Lancaster Av & Green St - MBNS to Syracuse Bus Station via West Chester Transit Center, 69th St Transit Center, 69th St Transit Center South Terminal, Chestnut St & 12th St, Philadelphia Bus Station, and Newark Penn Station in around 10h 44m.

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