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How to get fromDowntown Kansas City to Des Moinesby bus (Greyhound), car, or plane

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There are 3 ways to get from Downtown Kansas City to Des Moines by bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Kansas City to Des Moinesbus bus Jefferson Lines 804 / ...
    3h 25m
    $29–55
  2. Drive 192.3 mi

    1. Drive from Downtown Kansas City to Des Moinescar car 192.3 mi
    3h 13m
    $36–51
  3. Fly

    1. Fly from Kansas City (MCI) to Des Moines (DSM)plane plane MCI - DSM
    5h 42m
    $177–871

Downtown Kansas City to Des Moines by bus

Calendar23Weekly Buses
Duration3h 25mAverage Duration
Ticket$29Cheapest Price
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Questions & Answers

What companies run services between Downtown Kansas City, MO, USA and Des Moines, IA, USA?

Jefferson Lines operates a bus from Kansas City to Des Moines 3 times a day. Tickets cost $50–75 and the journey takes 3h 25m. Greyhound USA also services this route 5 times a week. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Kansas City (MCI) to Des Moines (DSM) hourly.

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