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How to get fromDowntown Tampa to Key Westby bus, plane, ferry, train, bus (Flixbus, Greyhound), car, or shuttle

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There are 10 ways to get from Downtown Tampa to Key West by bus, plane, ferry, train, bus (Flixbus, Greyhound), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 30 bus to Tampa, fly

    best
    1. Take the bus from Tyler St @ Franklin St to Airport Rental Car Facilitybus bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    3h 7m
    $83–405

  2. Line 300 bus to Saint Petersburg–Clearwater International Airport, fly

    cheapest
    1. Take the bus from Marion Transit Parking Lot to Psta 34Th St Complex - Shelter - Dbus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    3h 35m
    $51–258

  3. Bus, ferry

    1. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    10h 45m
    $153–173

  4. Train, bus

    1. Take the train from Tampa to Delray Beach Amtraktrain train
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    13h 3m
    $94–191

  5. Bus

    1. Take the bus from Tampa Bus Station to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    13h 16m
    $66–129

  6. Bus to Sarasota–Bradenton International Airport, fly

    1. Take the bus from Tampa Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Key West International Airport (EYW)plane plane SRQ - EYW
    6h 44m
    $522–932

  7. Drive to Orlando Sanford, fly

    1. Drive from Downtown Tampa to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3h 21m
    $65–291

  8. Train to Orlando, fly

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    5h 12m
    $104–718

  9. Bus, shuttle

    1. Take the bus from Tampa USF to Miami Airportbus bus Tallahassee–Miami via Tampa / ...
    2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus To the Keys
    13h 23m
    $246–348

  10. Drive 390.6 mi

    1. Drive from Downtown Tampa to Key Westcar car 390.6 mi
    8h 7m
    $72–103

Downtown Tampa to Key West by bus, foot, and ferry

Calendar7Weekly Services
Duration10h 45mAverage Duration
Ticket$153Cheapest Price
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Questions & Answers

Map of how to get from Downtown Tampa to Key West.ExpandLaunch map view
  • Distance: 252.4 mi
  • Duration: 3h 7m

What companies run services between Downtown Tampa, FL, USA and Key West, FL, USA?

You can take a bus from Tampa Bus Station to N Roosevelt & 3rd Street via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 13h 16m.

Airlines
Train operators
Bus operators
Ferry operators

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