There are 6 ways to get from Doylestown to St. Louis by train, plane, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Philadelphia International Airport, fly
best- Take the train from Doylestown to Suburban Stationtrain
- Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane PHL - STL
6h 14m$128–762Bus (Greyhound)
- Take the bus from Doylestown SEPTA Station to Philadelphia Bus Stationbus Greyhound US0340s
- Take the bus from Philadelphia Bus Station to St Louis Bus Stationbus Greyhound US0421
22h 10m$165–257Train
- Take the train from Doylestown to Jefferson Stationtrain Lan
- Take the train from 30th Street Station to Washington Union Stationtrain
- Take the train from Washington Union Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Louistrain
28h 20m$605–1,549Drive 885.2 mi
- Drive from Doylestown to St. Louiscar 885.2 mi
15h 13m$162–234Train, train to Baltimore-Washington International Airport, fly
- Take the train from Doylestown to Jefferson Stationtrain
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane BWI - STL
7h 27m$152–1,362Train, train to Ronald Reagan Washington National Airport, fly
- Take the train from Doylestown to Jefferson Stationtrain
- Take the train from 30th Street Station to Washington Union Stationtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane DCA - STL
8h 20m$172–1,099
Doylestown to St. Louis by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Doylestown to St. Louis is to bus which costs $160 - $260 and takes 22h 10m.
The fastest way to get from Doylestown to St. Louis is to train and fly which takes 6h 14m and costs $120 - $800.
No, there is no direct bus from Doylestown station to St. Louis station. However, there are services departing from Doylestown SEPTA Station and arriving at St Louis Bus Station via Philadelphia Bus Station. The journey, including transfers, takes approximately 22h 10m.
No, there is no direct train from Doylestown to St. Louis. However, there are services departing from Doylestown and arriving at St. Louis via 11th St, 30th Street Station, Washington Union Station and Chicago Union Station. The journey, including transfers, takes approximately 28h 20m.
The distance between Doylestown and St. Louis is 874 miles. The road distance is 890.4 miles.
The best way to get from Doylestown to St. Louis without a car is to bus which takes 22h 10m and costs $160 - $260.
It takes approximately 6h 14m to get from Doylestown to St. Louis, including transfers.
Doylestown to St. Louis bus services, operated by Greyhound USA, depart from Doylestown SEPTA Station.
Doylestown to St. Louis train services, operated by SEPTA, depart from Doylestown station.
The best way to get from Doylestown to St. Louis is to bus which takes 22h 10m and costs $160 - $260. Alternatively, you can train, which costs $600 - $1,600 and takes 28h 20m.
What companies run services between Doylestown, Bucks County, PA, USA and St. Louis, MO, USA?
You can take a bus from Doylestown SEPTA Station to St Louis Bus Station via Philadelphia Bus Station in around 22h 10m. Alternatively, you can take a train from Doylestown to St. Louis via Jefferson Station, 11th St, Drexel Station at 30th St, 30th Street Station, Washington Union Station, and Chicago Union Station in around 28h 20m.
- Website
- southwest.com
Flights from Philadelphia International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 28m
- When
- Every day
- Estimated price
- $150–800
Flights from Philadelphia International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 20m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $160–850
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 18m
- When
- Every day
- Estimated price
- $120–700
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport via Pittsburgh
- Ave. Duration
- 3h 50m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport via Cleveland
- Ave. Duration
- 4h
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–700
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 7m
- When
- Monday, Thursday, and Friday
- Estimated price
- $140–750
Flights from Ronald Reagan Washington National Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- $150–850
Flights from Ronald Reagan Washington National Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 7m
- When
- Tuesday, Monday, Thursday, and Friday
- Estimated price
- $170–900
Flights from Ronald Reagan Washington National Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 4h 20m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $170–950
- Website
- aa.com
Flights from Philadelphia International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $150–800
Flights from Ronald Reagan Washington National Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 39m
- When
- Every day
- Estimated price
- $150–850
- Website
- delta.com
Flights from Philadelphia International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $160–850
Flights from Baltimore-Washington International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $140–750
Flights from Ronald Reagan Washington National Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $170–900
- Phone
- +1 215-580-7800
- Website
- SEPTA
Train from Doylestown to Suburban Station
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Doylestown to Jefferson Station
- Ave. Duration
- 1h 22m
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Doylestown to Jefferson Station
- Ave. Duration
- 1h 22m
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Doylestown to Jefferson Station
- Ave. Duration
- 1h 22m
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $70–120
- Website
- Amtrak
Train from Washington Union Station to Chicago Union Station
- Ave. Duration
- 17h 48m
- Frequency
- Once daily
- Estimated price
- $420–650
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $70–120
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Doylestown SEPTA Station to Philadelphia Bus Station
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $4–7
- Website
- Greyhound
Bus from Philadelphia Bus Station to St Louis Bus Station
- Ave. Duration
- 20h 5m
- Frequency
- 3 times a day
- Estimated price
- $160–250
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Doylestown to St. Louis bus services, operated by Greyhound USA, arrive at Philadelphia Bus Station.
St. Louis is 1h behind Doylestown. It is currently 7:25 PM in Doylestown and 6:25 PM in St. Louis.
Doylestown to St. Louis train services, operated by SEPTA, arrive at Jefferson Station.
Yes, the driving distance between Doylestown to St. Louis is 890 miles. It takes approximately 15h 13m to drive from Doylestown to St. Louis.
Book your Doylestown to St. Louis bus tickets online with Omio and FlixBus.
There are 569+ hotels available in St. Louis.













