Rome2Rio

How to get fromDrake University to St. Louisby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Amtrak, Flixbus)

Find Transport to St. Louis

See all options

There are 6 ways to get from Drake University to St. Louis by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane plane DSM - STL
    4h 57m
    $118–671

  2. Drive  332.2 mi

    cheapest
    1. Drive from Drake University to St. Louiscar car 332.2 mi
    6h 42m
    $61–88

  3. Bus via Kansas City (Greyhound)

    1. Take the bus from Des Moines to Kansas City Bus Stationbus bus Greyhound US0156
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus Greyhound US0180s / ...
    8h 24m
    $75–141

  4. Bus, train via Kansas City

    1. Take the bus from Des Moines to Kansas City Bus Stationbus bus Greyhound US0156
    2. Take the train from Kansas City to St. Louistrain train Missouri River Runner / ...
    10h 45m
    $110–241

  5. Bus, train

    1. Take the bus from Des Moines to Bloomington-Normalbus bus Greyhound US0157S
    2. Take the train from Bloomington-Normal to St. Louistrain train Lincoln Service / ...
    10h 14m
    $93–191

  6. Bus

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    3. Take the bus from Springfield SMTD Transfer Center to St Louis Bus Stationbus bus
    10h 55m
    $92–145

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

Calendar136Weekly Planes
Duration5h 7mAverage Duration
Ticket$108Cheapest Price
See schedules

Questions & Answers

Map of how to get from Drake University to St. Louis.ExpandLaunch map view
  • Distance: 278.8 mi
  • Duration: 4h 57m

What companies run services between Drake University, IA, USA and St. Louis, MO, USA?

United Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a vehicle from Drake University to St Louis Bus Station via Des Moines and Kansas City Bus Station in around 8h 24m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers