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How to get fromDubuque to Knoxvilleby car, plane, bus (Flixbus), bus, or train

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There are 9 ways to get from Dubuque to Knoxville by car, plane, bus (Flixbus), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Quad City International Airport, fly

    best
    1. Drive from Dubuque to Moline-Airport-MLIcar car
    2. Fly from Quad City International Airport (MLI) to Mcghee Tyson Airport (TYS)plane plane MLI - TYS
    5h 51m
    $189–791

  2. Drive 703.7 mi

    cheapest
    1. Drive from Dubuque to Knoxvillecar car 703.7 mi
    12h 28m
    $129–186

  3. Bus via Farragut

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to New York Midtownbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    38h 45m
    $432–628

  4. Bus, train

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    42h 1m
    $552–1,009

  5. Drive to The Eastern Iowa Airport, fly

    1. Drive from Dubuque to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Mcghee Tyson Airport (TYS)plane plane CID - TYS
    6h
    $340–1,491

  6. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from Dubuque to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Mcghee Tyson Airport (TYS)plane plane MSN - TYS
    8h 40m
    $250–1,017

  7. Bus, train via Milwaukee

    1. Take the bus from Dubuque to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    4. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    42h 16m
    $525–954

  8. Bus

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    46h 9m
    $318–491

  9. Bus, train via Indianapolis

    1. Take the bus from Dubuque to Madisonbus bus
    2. Take the bus from Madison to Indianapolisbus bus
    3. Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    47h 44m
    $551–978

Quad City International Airport (MLI) to Mcghee Tyson Airport (TYS) flights

Calendar77Weekly Planes
Duration5h 23mAverage Duration
Ticket$127Cheapest Price
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Questions & Answers

Map of how to get from Dubuque to Knoxville.ExpandLaunch map view
  • Distance: 616.5 mi
  • Duration: 5h 51m

What companies run services between Dubuque, IA, USA and Knoxville, TN, USA?

You can take a bus from Dubuque to Knoxville via Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, Chicago Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 38h 45m.

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